Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 16/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6656946 | 1.00 | OPRD1 (0.44) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6654705 | 0.88 | OPRD1 (0.48) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6654713 | 0.88 | OPRD1 (0.48) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6652737 | 0.88 | OPRD1 (0.51) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6652740 | 0.88 | OPRD1 (0.51) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6654701 | 0.88 | OPRD1 (0.48) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6923990 | 0.82 | OPRD1 (0.54) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6652019 | 0.82 | OPRD1 (0.50) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6652027 | 0.82 | OPRD1 (0.50) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6652014 | 0.82 | OPRD1 (0.50) | OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983251-B1 | ANTI-INFLAMMATORY PIPERAZINYL-BENZYL-TETRAZOLE DERIVATIVES AND INTERMEDIATES THEREOF | PFIZER LTD (GB) | 2004-06-23 | — | — | EP | disclosed |