SCHEMBL6657147

SCHEMBL6657147

CCC(O)[C@@H](O)Oc1ccc(I)cc1

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 1/20 0.37
APP P05067 11/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
TRPA1 O75762 1/20 0.32
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6662309 0.81 LDHA (0.44) SLC6A4SMN1; SMN2
SCHEMBL6661078 0.81 LDHA (0.44) SLC6A4SMN1; SMN2
SCHEMBL6690262 0.81 LDHA (0.44) SLC6A4SMN1; SMN2
SCHEMBL28583037 0.80 TRPA1 (0.46) SLC6A4TRPA1
SCHEMBL255656 0.75 SLC6A4 (0.41) SLC6A4APP
SCHEMBL256374 0.74 ACACB (0.40) SLC6A4APP
SCHEMBL28981345 0.73 SLC6A4 (0.41) SLC6A4APP
SCHEMBL28772088 0.73 PARP10 (0.41) SLC6A4APP
Hydrochloric Acid SCHEMBL7379173 0.71 SLC6A4 (0.41) SLC6A4APPSMN1; SMN2
SCHEMBL5274970 0.70 SMN1; SMN2 (0.68) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1160233-B1 Novel terphenyl compounds SHARP KK (JP) 2004-07-21 EP disclosed
EP-1160233-A2 Novel terphenyl compounds SHARP KABUSHIKI KAISHA (JP) 2001-12-05 EP disclosed