Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6661078 | 1.00 | LDHA (0.44) | LDHAKDM4ETDP1MAPK1MEN1 | |
| SCHEMBL6662309 | 1.00 | LDHA (0.44) | LDHAKDM4ETDP1MAPK1MEN1 | |
| SCHEMBL6657147 | 0.81 | SLC6A4 (0.37) | SMN1; SMN2SLC6A4 | |
| SCHEMBL28583037 | 0.80 | TRPA1 (0.46) | ALDH1A1MAPTSLC6A4PPARGPPARA | |
| SCHEMBL6659807 | 0.76 | SLC6A4 (0.45) | SMN1; SMN2SLC6A4PPARGPPARAHPGD | |
| SCHEMBL12953262 | 0.75 | LDHA (0.45) | LDHAKDM4ETDP1MAPK1MEN1 | |
| SCHEMBL9966866 | 0.74 | LDHA (0.44) | LDHAKDM4ETDP1MEN1KMT2A | |
| SCHEMBL28334987 | 0.74 | LDHA (0.44) | LDHAKDM4ETDP1MEN1KMT2A | |
| SCHEMBL7966339 | 0.73 | LDHA (0.44) | LDHAKDM4ETDP1MAPK1MEN1 | |
| SCHEMBL6661442 | 0.73 | KDM4E (0.41) | LDHAKDM4ETDP1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1160233-B1 | Novel terphenyl compounds | SHARP KK (JP) | 2004-07-21 | — | — | EP | disclosed |
| EP-1160233-A2 | Novel terphenyl compounds | SHARP KABUSHIKI KAISHA (JP) | 2001-12-05 | — | — | EP | disclosed |