SCHEMBL6657434

SCHEMBL6657434

Nc1cccc(NCC(O)O)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DDX3X O00571 2/20 0.48
MAPT P10636 3/20 0.47
TDP1 Q9NUW8 2/20 0.47
KDM4E B2RXH2 1/20 0.47
MEN1 O00255 1/20 0.47
LMNA P02545 1/20 0.47
GAA P10253 1/20 0.47
GFER P55789 1/20 0.47
KMT2A Q03164 1/20 0.47
ALDH1A1 P00352 4/20 0.46
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HDAC9 Q9UKV0 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7174664 0.85 ALDH1A1 (0.47) DDX3XMAPTTDP1KDM4EMEN1
SCHEMBL15516467 0.81 MAPT (0.47) DDX3XMAPTTDP1KDM4EMEN1
SCHEMBL29922436 0.81 MAPT (0.47) DDX3XMAPTTDP1KDM4EMEN1
Hydrochloric Acid SCHEMBL28477179 0.80 AOC3 (0.50) MAPTTDP1KDM4EMEN1LMNA
SCHEMBL29922565 0.78 MAPT (0.44) DDX3XMAPTTDP1KDM4EMEN1
SCHEMBL21799995 0.78 MAPT (0.44) DDX3XMAPTTDP1KDM4EMEN1
SCHEMBL21799640 0.78 MAPT (0.44) DDX3XMAPTTDP1KDM4EMEN1
SCHEMBL29922614 0.78 MAPT (0.44) DDX3XMAPTTDP1KDM4EMEN1
SCHEMBL2492535 0.77 MAPT (0.62) MAPTKDM4EMEN1GAAKMT2A
SCHEMBL7753492 0.77 ADRB2 (0.49) MAPTMEN1LMNAGAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110951064-B Phthalocyanine metal salt modified polyurethane elastomer and preparation method thereof 南通北风橡塑制品有限公司 2021-08-27 CN claimed
CN-110951064-A Phthalocyanine metal salt modified polyurethane elastomer and preparation method thereof 南通北风橡塑制品有限公司 2020-04-03 CN claimed
CN-110951064-B Phthalocyanine metal salt modified polyurethane elastomer and preparation method thereof 南通北风橡塑制品有限公司 2021-08-27 CN disclosed
CN-110951064-A Phthalocyanine metal salt modified polyurethane elastomer and preparation method thereof 南通北风橡塑制品有限公司 2020-04-03 CN disclosed
EP-1047375-B2 TWO-PART HAIR DYE COMPOSITIONS CONTAINING POLYETHER POLYURETHANES AND CONDITIONING AGENTS P & G CLAIROL INC (US) 2013-12-11 EP disclosed
CN-1182830-C Two-part hair dye compositions containing polyether polyurethanes and conditioning agents 2005-01-05 CN disclosed
EP-1047375-B1 TWO-PART HAIR DYE COMPOSITIONS CONTAINING POLYETHER POLYURETHANES AND CONDITIONING AGENTS P & G CLAIROL INC (US) 2004-11-03 EP disclosed
EP-0891765-B1 Oxidative hair dye compositions P & G CLAIROL INC (US) 2004-06-16 EP disclosed
US-20030140430-A1 Two-part hair dye compositions containing polyether polyurethanes and conditiong agents CASPERSON STEPHEN (US) 2003-07-31 US disclosed
CN-1285736-A Two-part hair dye compositions containing polyether polyurethanes and conditioning agents BRISTOL MYES SQUIBB CO (US) 2001-02-28 CN disclosed
US-6156076-A Two-part hair dye compositions containing polyether polyurethanes and conditioning agents BRISTOL-MYERS SQUIBB COMPANY (US) 2000-12-05 US disclosed
EP-1047375-A1 TWO-PART HAIR DYE COMPOSITIONS CONTAINING POLYETHER POLYURETHANES AND CONDITIONING AGENTS Bristol-Myers Squibb Company (US) 2000-11-02 EP disclosed
WO-1999036047-A1 TWO-PART HAIR DYE COMPOSITIONS CONTAINING POLYETHER POLYURETHANES AND CONDITIONING AGENTS BRISTOL-MYERS SQUIBB COMPANY (US) 1999-07-22 WO disclosed
EP-0891765-A2 Oxidative hair dye compositions Bristol-Myers Squibb Company (US) 1999-01-20 EP disclosed
US-5851237-A Oxidative hair dye compositions and methods containing 1--(4-aminophenyl) pyrrolidines NOXELL CORPORATION 1998-12-22 US disclosed