SCHEMBL6657740

SCHEMBL6657740

c1ccc(N=Nc2cccc(N=Nc3ccccc3)c2N=Nc2ccccc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.60
CASP3 P42574 2/20 0.48
SENP7 Q9BQF6 2/20 0.48
SENP6 Q9GZR1 2/20 0.48
SENP8 Q96LD8 1/20 0.48
MEN1 O00255 6/20 0.46
KMT2A Q03164 6/20 0.46
MAPT P10636 6/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
PKM P14618 1/20 0.46
HTT P42858 1/20 0.46
TDP1 Q9NUW8 6/20 0.45
MAPK1 P28482 5/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
MAOA P21397 1/20 0.45
MAOB P27338 1/20 0.45
CYP3A4 P08684 3/20 0.44
TSHR P16473 3/20 0.44
HBB P68871 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27575424 0.85 THRB (0.53) ALDH1A1CASP3SENP7SENP6SENP8
SCHEMBL3266656 0.84 ALDH1A1 (0.75) ALDH1A1CASP3SENP7SENP6SENP8
SCHEMBL28126627 0.83 CASP3 (0.63) ALDH1A1CASP3SENP7SENP6SENP8
SCHEMBL10408855 0.81 ALDH1A1 (0.80) ALDH1A1CASP3SENP7SENP6SENP8
SCHEMBL11130604 0.78 THRB (0.58) ALDH1A1CASP3SENP7SENP6SENP8
Azobenzene SCHEMBL6562161 0.78 ALDH1A1 (1.00) ALDH1A1CASP3SENP7SENP6SENP8
Azobenzene SCHEMBL6703357 0.78 ALDH1A1 (1.00) ALDH1A1CASP3SENP7SENP6SENP8
Azobenzene SCHEMBL11124477 0.78 ALDH1A1 (1.00) ALDH1A1CASP3SENP7SENP6SENP8
Azobenzene SCHEMBL32032 0.78 ALDH1A1 (1.00) ALDH1A1CASP3SENP7SENP6SENP8
Azobenzene SCHEMBL565791 0.78 ALDH1A1 (1.00) ALDH1A1CASP3SENP7SENP6SENP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0456659-B1 CHARGE DIRECTOR COMPOSITION HEWLETT PACKARD INDIGO BV (NL) 2004-06-30 EP disclosed
EP-0472627-B1 HUMIDITY TOLERANT CHARGE DIRECTOR COMPOSITIONS INDIGO NV (NL) 1996-01-10 EP disclosed
US-5286593-A Liquid developer containing stabilized charge director composition SPECTRUM SCIENCES B.V. (NL) 1994-02-15 US disclosed
US-5264313-A Lecithin is stqbilized by polyvinylpyrrolidone polymer; useful for forming electronstatic images SPECTRUM SCIENCES B.V. (NL) 1993-11-23 US disclosed
EP-0472627-A1 HUMIDITY TOLERANT CHARGE DIRECTOR COMPOSITIONS. SPECTRUM SCIENCES BV (NL) 1992-03-04 EP disclosed
EP-0456659-A1 CHARGE DIRECTOR COMPOSITION INDIGO N.V. (NL) 1991-11-21 EP disclosed
US-5047306-A Humidity tolerant charge director compositions SPECTRUM SCIENCES B. V. (NL) 1991-09-10 US disclosed
WO-1990014617-A1 HUMIDITY TOLERANT CHARGE DIRECTOR COMPOSITIONS SPECTRUM SCIENCES B.V. (NL) 1990-11-29 WO disclosed
WO-1990008983-A1 CHARGE DIRECTOR COMPOSITION SAVIN CORPORATION (US) 1990-08-09 WO disclosed
US-4401742-A POLYMERIZATION, WITH ESTERIFICATION OF AN ALCOHOLIC DISPERSANT PITNEY BOWES INC. (US) 1983-08-30 US disclosed