SCHEMBL665776

SCHEMBL665776

O=C(O)CC(O)CCOc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP12 P39900 3/20 0.54
MMP13 P45452 2/20 0.54
MMP2 P08253 1/20 0.50
MMP9 P14780 1/20 0.50
MMP14 P50281 1/20 0.50
ALOX15 P16050 1/20 0.50
PKM P14618 1/20 0.49
PPARG P37231 1/20 0.48
PPARA Q07869 1/20 0.48
TDP1 Q9NUW8 2/20 0.47
RECQL P46063 2/20 0.47
ALDH1A1 P00352 2/20 0.47
CYP1A2 P05177 1/20 0.47
ADRB2 P07550 1/20 0.47
ADRB1 P08588 1/20 0.47
ADRB3 P13945 1/20 0.47
KCNA3 P22001 1/20 0.47
POLB P06746 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
PARP10 Q53GL7 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4748340 1.00 MMP12 (0.54) MMP12MMP13MMP2MMP9MMP14
SCHEMBL1139604 0.91 TDP1 (0.54) MMP12MMP13MMP2MMP9MMP14
SCHEMBL5498859 0.91 MMP12 (0.67) MMP12MMP13MMP2MMP9MMP14
SCHEMBL1067167 0.90 KCNA3 (0.53) MMP12MMP13MMP2MMP9MMP14
SCHEMBL1065894 0.88 KCNA3 (0.52) MMP12MMP13MMP2MMP9MMP14
SCHEMBL1138982 0.88 KCNA3 (0.52) MMP12MMP13MMP2MMP9MMP14
SCHEMBL1066086 0.88 KCNA3 (0.52) MMP12MMP13MMP2MMP9MMP14
SCHEMBL4403318 0.85 MMP12 (0.47) MMP12MMP13TDP1POLBL3MBTL1
SCHEMBL4257609 0.85 L3MBTL1 (0.60) MMP12MMP13PPARGPPARATDP1
SCHEMBL4655066 0.83 RAB9A (0.50) PKMPPARGPPARATDP1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 273 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9957533-B2 Mutant of propionyl-CoA transferase from Clostridium propionicum and preparing method for PLA or PLA copolymer using the same LG CHEM, LTD. (KR) 2018-05-01 US claimed
US-9920338-B2 Recombinant Ralstonia eutropha capable of producing polylactic acid or polylatic acid polymer, and method for producing polylactic acid or polylatic acid copolymer using same LG CHEM, LTD. (KR) 2018-03-20 US claimed
EP-2089522-B1 MUTANTS OF PHA SYNTHASE FROM PSEUDOMONAS SP.6-19 AND METHOD FOR PREPARING LACTATE HOMOPOLYMER OR COPOLYMER USING THE SAME LG CHEMICAL LTD (KR) 2017-11-01 EP claimed
EP-2650372-B1 Preparation method of lactate polymers and lactate copolymers using polyhydroxyalkanoate synthase mutants LG CHEMICAL LTD (KR) 2017-03-01 EP claimed
US-20160312251-A1 MUTANT OF PROPIONYL-COA TRANSFERASE FROM CLOSTRIDIUM PROPIONICUM AND PREPARING METHOD FOR PLA OR PLA COPOLYMER USING THE SAME LG CHEM, LTD. (KR) 2016-10-27 US claimed
US-9410167-B2 Cells or plants producing polylactate or its copolymers and uses thereof LG CHEM, LTD. (KR) 2016-08-09 US claimed
US-20160177348-A1 RECOMINANT RALSTONIA EUTROPHA CAPABLE OF PRODUCING POLYLACTIC ACID OR POLYLATIC ACID POLYMER, AND METHOD FOR PRODUCING POLYLACTIC ACID OR POLYLATIC ACID COPOLYMER USING SAME LG CHEM, LTD. (KR) 2016-06-23 US claimed
US-9243265-B2 Recominant Ralstonia eutropha capable of producing polyactic and acid or polylatic acid polymer, and method for producing polyactic acid or polylatic acid copolymer using the same LG CHEM, LTD. (KR) 2016-01-26 US claimed
EP-2636744-B1 MUTANT OF PROPIONYL-COA TRANSFERASE FROM CLOSTRIDIUM PROPIONICUM AND PREPARING METHOD FOR PLA OR PLA COPOLYMER USING THE SAME LG CHEMICAL LTD (KR) 2015-04-08 EP claimed
US-20150031098-A1 MUTANT OF PROPIONYL-COA TRANSFERASE FROM CLOSTRIDIUM PROPIONICUM AND PREPARING METHOD FOR PLA OR PLA COPOLYMER USING THE SAME LG CHEM, LTD. (KR) 2015-01-29 US claimed
US-20060172394-A1 Polyhydroxyalkanoate synthesizing microorganism and process of producing polyhydroxyalkanoate using the same CANON KABUSHIKI KAISHA (JP) 2006-08-03 US claimed
US-20040067576-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2004-04-08 US claimed
US-20030208029-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2003-11-06 US claimed
US-20030180899-A1 Process for producing polyhydroxyalkanoates by utilizing microorganisms HONMA TSUTOMU (JP) 2003-09-25 US claimed
US-6586562-B2 Polylactone with units such as of 3-hydroxy-5-(4-fluorophenyl)valeric acid; biosynthesis of the polylactone by microorganism; Pseudomonas cichorii; P. putida; P. jessenii CANON KABUSHIKI KAISHA (JP) 2003-07-01 US claimed
US-6521429-B2 Using culture media and yeast extracts CANON KABUSHIKI KAISHA (JP) 2003-02-18 US claimed
US-20020022253-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2002-02-21 US claimed
US-20010029039-A1 Polyhydroxyalkanoates and method of producing them by utilizing mircroorganisms CANON KABUSHIKI KAISHA (JP) 2001-10-11 US claimed
EP-1118629-A2 Polyhydroxyalkanoates and method of producing them by utilizing microorganisms CANON KABUSHIKI KAISHA (JP) 2001-07-25 EP claimed
EP-1113033-A2 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2001-07-04 EP claimed