SCHEMBL6658205

SCHEMBL6658205

CCCNc1cc(OC)c2c(c1O)C(C)(C)C(=O)N2

nearest known ligand 0.32

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FLI1 Q01543 1/20 0.32
EWSR1 Q01844 1/20 0.32
PDK2 Q15119 2/20 0.31
PDK1 Q15118 1/20 0.31
PDK3 Q15120 1/20 0.31
PDK4 Q16654 1/20 0.31
LMNA P02545 1/20 0.31
ALDH1A1 P00352 2/20 0.31
APAF1 O14727 1/20 0.31
TDP2 O95551 1/20 0.31
GAA P10253 1/20 0.31
MAPK1 P28482 1/20 0.31
CASP3 P42574 1/20 0.31
SENP8 Q96LD8 1/20 0.31
HSD17B10 Q99714 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31
FYN P06241 1/20 0.30
MOGAT2 Q3SYC2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6659302 0.82 CISD1 (0.36) FLI1EWSR1PDK2PDK1PDK3
SCHEMBL6659420 0.82 LMNA (0.34) LMNAALDH1A1GAA
SCHEMBL6384278 0.81 HTT (0.45) ALDH1A1MAPK1HSD17B10
SCHEMBL6384389 0.80 MEN1 (0.40) LMNAALDH1A1GAAMAPK1HSD17B10
SCHEMBL6658731 0.76 DRD2 (0.35) ALDH1A1
SCHEMBL6658183 0.74 ADRB3 (0.35) LMNAALDH1A1APAF1TDP2GAA
SCHEMBL6661841 0.72 IDO1 (0.38) PDK2PDK1PDK3PDK4LMNA
SCHEMBL6655341 0.64 LMNA (0.35) LMNA
SCHEMBL6384739 0.63 CYP3A4 (0.38) LMNAALDH1A1MAPK1HSD17B10
SCHEMBL21284586 0.63 HMGCR (0.44) ALDH1A1GAAHSD17B10FYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1438949-A1 Composition for dyeing keratinous fibres comprising an acylaminophenol coupler L'OREAL (FR) 2004-07-21 EP claimed
EP-1438949-A1 Composition for dyeing keratinous fibres comprising an acylaminophenol coupler L'OREAL (FR) 2004-07-21 EP disclosed