Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | FABP3 | P05413 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25565205 | 0.88 | L3MBTL1 (0.47) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL6658293 | 0.81 | KMT2A (0.40) | ALDH1A1HPGDKMT2ATHRBGSR | |
| SCHEMBL29657033 | 0.81 | THRB (0.42) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL28910060 | 0.80 | HPGD (0.40) | KDM4EALDH1A1HPGDKMT2ATHRB | |
| SCHEMBL28624346 | 0.80 | KMT2A (0.39) | ALDH1A1HPGDKMT2AL3MBTL1THRB | |
| SCHEMBL28134133 | 0.80 | HSD17B10 (0.39) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL28954462 | 0.80 | ALDH1A1 (0.39) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL28133169 | 0.80 | KDM4E (0.39) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL20534013 | 0.80 | KMT2A (0.39) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL27730838 | 0.80 | BCL2A1 (0.38) | ALDH1A1HPGDKMT2ATHRBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116234798-A | Sulfamate derivative compounds for the treatment or alleviation of psychotic disorders | 生物药品解决方案有限公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-106507667-B | Sulfamate derivatives for the prevention or treatment of epilepsy | 比皮艾思药物研发有限公司 | 2020-01-24 | — | — | CN | disclosed |
| CN-106456599-B | For treating or mitigating the sulphamate derivs compound of pain | 比皮艾思药物研发有限公司 | 2019-05-14 | — | — | CN | disclosed |
| CN-106456599-A | Sulfamate derivative compounds for use in treating or alleviating pain | 比皮艾思药物研发有限公司 | 2017-02-22 | — | — | CN | disclosed |
| US-4835312-A | Production process of N-substituted amide compounds | MITSUI CHEMICALS, INCORPORATED (JP) | 1989-05-30 | — | — | US | disclosed |