Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 13/20 | 0.44 |
| ▸ | CTSS | P25774 | 10/20 | 0.41 |
| ▸ | CTSK | P43235 | 9/20 | 0.41 |
| ▸ | CTSB | P07858 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6497579 | 0.84 | CTSS (0.53) | CTSLCTSSCTSKCTSB | |
| SCHEMBL8258105 | 0.83 | CTSS (0.41) | CTSLCTSSCTSKCTSB | |
| SCHEMBL6836812 | 0.82 | CTSS (0.40) | CTSLCTSSCTSKCTSB | |
| SCHEMBL6836920 | 0.82 | CTSL (0.40) | CTSLCTSSCTSKCTSB | |
| SCHEMBL6836041 | 0.81 | CTSS (0.42) | CTSLCTSSCTSKCTSB | |
| SCHEMBL6503499 | 0.81 | MAOB (0.35) | CTSL | |
| SCHEMBL6503503 | 0.81 | MAOB (0.35) | CTSL | |
| SCHEMBL8258089 | 0.81 | CTSS (0.44) | CTSLCTSSCTSKCTSB | |
| SCHEMBL6832872 | 0.80 | CTSL (0.39) | CTSLCTSSCTSKCTSB | |
| SCHEMBL6836731 | 0.80 | CTSL (0.39) | CTSLCTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1434769-A2 | COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2004-07-07 | — | — | EP | disclosed |
| WO-2003029200-A2 | COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2003-04-10 | — | — | WO | disclosed |