Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 12/20 | 0.42 |
| ▸ | CTSK | P43235 | 8/20 | 0.42 |
| ▸ | CTSB | P07858 | 6/20 | 0.42 |
| ▸ | CTSL | P07711 | 8/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6836712 | 0.93 | CTSL (0.38) | CTSSCTSKCTSBCTSL | |
| SCHEMBL7685576 | 0.93 | CTSL (0.38) | CTSSCTSKCTSBCTSL | |
| SCHEMBL8256796 | 0.92 | CTSS (0.44) | CTSSCTSKCTSBCTSL | |
| SCHEMBL6832872 | 0.92 | CTSL (0.39) | CTSSCTSKCTSBCTSL | |
| SCHEMBL6836731 | 0.92 | CTSL (0.39) | CTSSCTSKCTSBCTSL | |
| SCHEMBL6837095 | 0.91 | CTSL (0.37) | CTSSCTSKCTSBCTSL | |
| SCHEMBL6836067 | 0.91 | CTSK (0.39) | CTSSCTSKCTSBCTSL | |
| SCHEMBL6832858 | 0.91 | CTSL (0.37) | CTSSCTSKCTSBCTSL | |
| SCHEMBL6838761 | 0.91 | SMN1; SMN2 (0.42) | CTSSCTSKCTSBCTSL | |
| SCHEMBL6836868 | 0.90 | CTSL (0.36) | CTSSCTSKCTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040006078-A1 | Compounds useful as reversible inhibitors of cysteine proteases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2004-01-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006078-A1 | Compounds useful as reversible inhibitors of cysteine proteases | CTSS, CTSK, CTSB | CTSS 1/4885CTSK 2/4885CTSB 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.