SCHEMBL6658640

SCHEMBL6658640

Cc1cccc(-c2c(C)cc(N)cc2O)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 7/20 0.49
CNR1 P21554 5/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
ACLY P53396 1/20 0.44
RAB9A P51151 2/20 0.42
ACHE P22303 2/20 0.41
TSHR P16473 1/20 0.41
CASP1 P29466 1/20 0.41
PDE10A Q9Y233 1/20 0.41
HEXA P06865 1/20 0.41
HEXB P07686 1/20 0.41
ALDH1A1 P00352 3/20 0.41
HSD17B10 Q99714 2/20 0.41
NPC1 O15118 1/20 0.41
TP53 P04637 1/20 0.41
POLB P06746 1/20 0.41
HPGD P15428 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9848294 0.82 RAB9A (0.44) CNR2CNR1L3MBTL1RAB9AACHE
SCHEMBL23309016 0.76 ACHE (0.52) CNR2CNR1L3MBTL1ACLYRAB9A
SCHEMBL27750360 0.76 MKNK1 (0.47) L3MBTL1ACLYRAB9AALDH1A1HSD17B10
SCHEMBL5684819 0.75 CNR2 (0.54) CNR2CNR1RAB9AACHETSHR
SCHEMBL2936454 0.75 CNR2 (0.51) CNR2CNR1L3MBTL1ACLYRAB9A
SCHEMBL31236143 0.75 ACHE (0.52) CNR2CNR1L3MBTL1RAB9AACHE
Hydrochloric Acid SCHEMBL5688030 0.74 CNR2 (0.53) CNR2CNR1RAB9AACHETSHR
SCHEMBL27729959 0.74 IMPDH2 (0.43) TSHRCASP1PDE10AALDH1A1SMN1; SMN2
SCHEMBL26032118 0.73 ACHE (0.50) CNR2CNR1L3MBTL1ACLYRAB9A
SCHEMBL9681062 0.72 RAB9A (0.48) CNR2CNR1L3MBTL1RAB9AACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1418879-A1 OXIDATION HAIR DYES CONTAINING 3-AMINOPHENOL DERIVATIVES, AND NOVEL 3-AMINOPHENOL DERIVATIVES Wella Aktiengesellschaft (DE) 2004-05-19 EP disclosed
WO-2003017955-A1 OXIDATION HAIR DYES CONTAINING 3-AMINOPHENOL DERIVATIVES, AND NOVEL 3-AMINOPHENOL DERIVATIVES WELLA AKTIENGESELLSCHAFT (DE) 2003-03-06 WO disclosed