SCHEMBL6658752

SCHEMBL6658752

CCCCC(CC)Cc1ccc(Cc2cc(C(=O)O)ccc2C(=O)O)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.45
ALDH1A1 P00352 4/20 0.44
MAPK1 P28482 1/20 0.44
PPARA Q07869 1/20 0.41
RARB P10826 8/20 0.39
CYP3A4 P08684 2/20 0.38
CA2 P00918 1/20 0.38
MEN1 O00255 1/20 0.37
RARA P10276 1/20 0.37
MAPT P10636 1/20 0.37
MTOR P42345 1/20 0.37
KMT2A Q03164 1/20 0.37
GRIN2D O15399 1/20 0.37
GRIN2A Q12879 1/20 0.37
GRIN2B Q13224 1/20 0.37
GRIN2C Q14957 1/20 0.37
LMNA P02545 1/20 0.37
HSD17B10 Q99714 1/20 0.37
PTPN11 Q06124 1/20 0.37
BDKRB2 P30411 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6057021 0.90 ALDH1A1 (0.44) TSHRALDH1A1MAPK1PPARARARB
SCHEMBL6653637 0.88 KDM4E (0.50) TSHRALDH1A1MAPK1PPARARARB
SCHEMBL6690303 0.87 ALDH1A1 (0.50) TSHRALDH1A1MAPK1PPARACYP3A4
SCHEMBL9700188 0.84 RARB (0.53) TSHRALDH1A1MAPK1RARBCYP3A4
SCHEMBL6056990 0.84 BDKRB2 (0.45) TSHRALDH1A1MAPK1PPARARARB
SCHEMBL9988562 0.83 TSHR (0.46) TSHRALDH1A1MAPK1PPARARARB
SCHEMBL812197 0.81 ALDH1A1 (0.49) TSHRALDH1A1MAPK1PPARARARB
SCHEMBL28837472 0.80 PPARA (0.48) TSHRALDH1A1MAPK1PPARARARB
SCHEMBL30001700 0.80 PPARA (0.48) TSHRALDH1A1MAPK1PPARARARB
SCHEMBL11658538 0.80 RARB (0.60) ALDH1A1RARBMEN1RARAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1592729-A Process for preparing pentacene derivatives 3M INNOVATIVE PROPERTIES CO (US) 2005-03-09 CN disclosed
CN-1582506-A Substituted pentacene semiconductors 3M INNOVATIVE PROPERTIES CO (US) 2005-02-16 CN disclosed
EP-1433211-A2 SUBSTITUTED PENTACENE SEMICONDUCTORS 3M Innovative Properties Company (US) 2004-06-30 EP disclosed
EP-1430008-A2 PROCESS FOR PREPARING PENTACENE DERIVATIVES 3M Innovative Properties Company (US) 2004-06-23 EP disclosed
WO-2003028125-A2 SUBSTITUTED PENTACENE SEMICONDUCTORS 3M INNOVATIVE PROPERTIES COMPANY (US) 2003-04-03 WO disclosed
WO-2003027050-A2 PROCESS FOR PREPARING PENTACENE DERIVATIVES 3M INNOVATIVE PROPERTIES COMPANY (US) 2003-04-03 WO disclosed