Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28121432 | 0.90 | ALDH1A1 (0.51) | ALDH1A1TSHRMAPK1CA2PPARA | |
| SCHEMBL6690303 | 0.87 | ALDH1A1 (0.50) | ALDH1A1TSHRMAPK1CA2PPARA | |
| SCHEMBL19816020 | 0.84 | PTGER4 (0.45) | TSHRPPARAPTPN11RARBTP53 | |
| SCHEMBL9988562 | 0.83 | TSHR (0.46) | ALDH1A1TSHRMAPK1PPARAPTPN11 | |
| SCHEMBL459872 | 0.82 | GABRP (0.54) | ALDH1A1TSHRPPARAPTPN11RARB | |
| SCHEMBL19817501 | 0.82 | PLA2G4B (0.43) | TSHRPPARAPTPN11RARBTP53 | |
| SCHEMBL6658752 | 0.81 | TSHR (0.45) | ALDH1A1TSHRMAPK1CA2PPARA | |
| SCHEMBL19819329 | 0.81 | PTGER4 (0.44) | ALDH1A1PPARAPTPN11RARBGABRP | |
| SCHEMBL28745786 | 0.81 | ALDH1A1 (0.52) | ALDH1A1TSHRMAPK1CA2PPARA | |
| SCHEMBL7934928 | 0.81 | RARB (0.54) | ALDH1A1TSHRPPARAPTPN11RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2689643-A1 | THERMAL MANAGEMENT WITHIN AN LED ASSEMBLY | Dow Corning Corporation (US) | 2014-01-29 | — | — | EP | claimed |
| US-20130344632-A1 | Thermal Management Within an LED Assembly | DOW CORNING CORPORATION (US) | 2013-12-26 | — | — | US | claimed |
| US-8440312-B2 | Thermal interface materials and methods for their preparation and use | DOW CORNING CORPORATION (US) | 2013-05-14 | — | — | US | claimed |
| WO-2012128875-A1 | THERMAL MANAGEMENT WITHIN AN LED ASSEMBLY | DOW CORNING CORPORATION (US) | 2012-09-27 | — | — | WO | claimed |
| EP-2406321-A1 | THERMAL INTERFACE MATERIALS AND METHODS FOR THEIR PREPARATION AND USE | Dow Corning Corporation (US) | 2012-01-18 | — | — | EP | claimed |
| US-20110311767-A1 | Thermal Interface Materials and Methods for Their Preparation and Use | DOW CORNING CORPORATION | 2011-12-22 | — | — | US | claimed |
| WO-2010104534-A1 | THERMAL INTERFACE MATERIALS AND MEHTODS FOR THEIR PREPARATION AND USE | DOW CORNING CORPORATION (US) | 2010-09-16 | — | — | WO | claimed |
| EP-4519346-B1 | SILICONE-POLYETHER COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS | DOW SILICONES CORP (US) | 2026-01-14 | — | — | EP | disclosed |
| US-12428561-B2 | Silicone-polyether copolymer, sealants comprising same, and related methods | DOW SILICONES CORPORATION (US) | 2025-09-30 | — | — | US | disclosed |
| US-20250257169-A1 | COMPOSITION, URETHANE PREPOLYMER, AND RELATED METHODS AND USES | DOW SILICONES CORP (US) | 2025-08-14 | — | — | US | disclosed |
| US-12378264-B2 | Multifunctional organosilicon compound and related methods, compounds, and compositions | DOW SILICONES CORPORATION (US) | 2025-08-05 | — | — | US | disclosed |
| US-12344712-B2 | Silicone-poly acrylate copolymer, sealants comprising same, and related methods | DOW SILICONES CORPORATION (US) | 2025-07-01 | — | — | US | disclosed |
| EP-3898782-B1 | SILICONE-POLYACRYLATE COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS | DOW SILICONES CORP (US) | 2025-06-25 | — | — | EP | disclosed |
| WO-2012134786-A1 | COMPOSITIONS CONTINING SULFONIC ACID CATALYSTS AND METHODS FOR THE PREPARATION AND USE OF THE COMPOSITIONS | DOW CORNING CORPORATION (US) | 2012-10-04 | — | — | WO | disclosed |
| WO-2012134784-A1 | COMPOSITIONS CONTAINING PHOSPHONATE CATALYSTS AND METHODS FOR THE PREPARATION AND USE OF THE COMPOSITIONS | DOW CORNING CORPORATION (US) | 2012-10-04 | — | — | WO | disclosed |
| WO-2012128875-A1 | THERMAL MANAGEMENT WITHIN AN LED ASSEMBLY | DOW CORNING CORPORATION (US) | 2012-09-27 | — | — | WO | disclosed |
| EP-2406321-A1 | THERMAL INTERFACE MATERIALS AND METHODS FOR THEIR PREPARATION AND USE | Dow Corning Corporation (US) | 2012-01-18 | — | — | EP | disclosed |
| US-20110311767-A1 | Thermal Interface Materials and Methods for Their Preparation and Use | DOW CORNING CORPORATION | 2011-12-22 | — | — | US | disclosed |
| WO-2011072056-A2 | CURE RATE CONTROL FOR ALKOXYSILYL-END-BLOCKED POLYMERS | DOW CORNING COPORATION (US) | 2011-06-16 | — | — | WO | disclosed |
| WO-2010104534-A1 | THERMAL INTERFACE MATERIALS AND MEHTODS FOR THEIR PREPARATION AND USE | DOW CORNING CORPORATION (US) | 2010-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12378264-B2 | Multifunctional organosilicon compound and related methods, compounds, and compositions | MSR1, OXSR1, RIOX2 | ALDH1A1 1749/4885TSHR 2322/4885MAPK1 4154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.