Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 13/20 | 0.65 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ANPEP | P15144 | 1/20 | 0.52 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL315781 | 0.93 | ALDH1A1 (0.60) | SRD5A2FOLH1ALDH1A1TP53TSHR | |
| SCHEMBL10645186 | 0.91 | ALDH1A1 (0.58) | SRD5A2FOLH1ALDH1A1TP53TSHR | |
| SCHEMBL1200737 | 0.91 | SRD5A2 (0.48) | SRD5A2FOLH1ALDH1A1 | |
| SCHEMBL4541127 | 0.87 | ALDH1A1 (0.61) | SRD5A2FOLH1ALDH1A1 | |
| SCHEMBL15025047 | 0.83 | SRD5A2 (0.41) | SRD5A2FOLH1ALDH1A1 | |
| SCHEMBL8091787 | 0.81 | IDO1 (0.67) | SRD5A2ALDH1A1TSHR | |
| SCHEMBL2407327 | 0.81 | SRD5A2 (1.00) | SRD5A2ALDH1A1TP53TSHR | |
| SCHEMBL69729 | 0.81 | SRD5A2 (1.00) | SRD5A2ALDH1A1TP53TSHR | |
| Benzoic Acid SCHEMBL28076089 | 0.80 | FOLH1 (0.70) | SRD5A2FOLH1TP53TSHRANPEP | |
| SCHEMBL10654851 | 0.78 | SRD5A2 (0.65) | SRD5A2ALDH1A1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888389-B1 | PHOTOACTIVATABLE CHAIN TRANSFER AGENTS | SURMODICS INC (US) | 2004-08-04 | — | — | EP | disclosed |
| EP-0888389-A4 | PHOTOACTIVATABLE CHAIN TRANSFER AGENTS | SURMODICS INC (US) | 2001-03-14 | — | — | EP | disclosed |
| US-5942555-A | Photoactivatable chain transfer agents and semi-telechelic photoactivatable polymers prepared therefrom | SURMODICS, INC. (US) | 1999-08-24 | — | — | US | disclosed |
| EP-0888389-A1 | PHOTOACTIVATABLE CHAIN TRANSFER AGENTS | SurModics, Inc. (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997034935-A1 | PHOTOACTIVATABLE CHAIN TRANSFER AGENTS | BSI CORPORATION (US) | 1997-09-25 | — | — | WO | disclosed |