SCHEMBL315781

SCHEMBL315781

O=C(O)c1ccc(CS)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.60
TSHR P16473 2/20 0.60
TP53 P04637 1/20 0.60
FOLH1 Q04609 4/20 0.59
ANPEP P15144 2/20 0.57
ENPEP Q07075 1/20 0.57
SRD5A2 P31213 2/20 0.52
KMT2A Q03164 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA12 O43570 1/20 0.50
CA3 P07451 1/20 0.50
TYR P14679 1/20 0.50
DRD1 P21728 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10645186 0.98 ALDH1A1 (0.58) ALDH1A1TSHRTP53FOLH1ANPEP
SCHEMBL6659142 0.93 SRD5A2 (0.65) ALDH1A1TSHRTP53FOLH1ANPEP
Benzoic Acid SCHEMBL28076089 0.86 FOLH1 (0.70) TSHRTP53FOLH1ANPEPENPEP
SCHEMBL14234617 0.82 CES2 (0.50) FOLH1KMT2A
SCHEMBL1200737 0.82 SRD5A2 (0.48) ALDH1A1FOLH1SRD5A2KMT2AMAPT
SCHEMBL13531601 0.81 PTPRC (0.55) ALDH1A1FOLH1ANPEPENPEP
SCHEMBL1493657 0.81 ALDH1A1 (0.56) ALDH1A1TSHRTP53FOLH1ANPEP
SCHEMBL6050896 0.79 CES2 (0.65) ALDH1A1FOLH1CA1CA2CA12
SCHEMBL4541127 0.79 ALDH1A1 (0.61) ALDH1A1FOLH1SRD5A2KMT2AMEN1
SCHEMBL68390 0.79 SRD5A2 (0.69) ALDH1A1TSHRTP53SRD5A2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12338434-B1 Methods and materials for discovery of functional ligands to molecular complexes Base Pair Biotechnologies, Inc. (US) 2025-06-24 US claimed
CN-118026938-B Pyrazolone ester compound and electrochemical synthesis method thereof 江西本草天工科技有限责任公司 2024-06-28 CN claimed
CN-118026938-A Pyrazolone ester compound and electrochemical synthesis method thereof 江西本草天工科技有限责任公司 2024-05-14 CN claimed
WO-2023032208-A1 NANOPARTICLE COMPOSITION, NANOPARTICLE-CONTAINING FILM, LIGHT EMITTING ELEMENT, WAVELENGTH CONVERSION MEMBER, DISPLAY DEVICE AND METHOD FOR PRODUCING NANOPARTICLE-CONTAINING FILM シャープ株式会社 2023-03-09 WO claimed
US-20070197577-A1 Inhibitors of anthrax lethal factor CENGENT THERAPEUTICS (US) 2007-08-23 US claimed
WO-2005027856-A2 INHIBITORS OF ANTHRAX LETHAL FACTOR CENGENT THERAPEUTICS (US) 2005-03-31 WO claimed
EP-1057034-A1 ASSAY FOR DETECTION OF PHOSPHATE OR CARBOHYDRATE GROUPS ON SERINE RESIDUES THE UNIVERSITY OF NEWCASTLE RESEARCH ASSOCIATES LIMITED (AU) 2000-12-06 EP claimed
WO-1999038012-A1 ASSAY FOR DETECTION OF PHOSPHATE OR CARBOHYDRATE GROUPS ON SERINE RESIDUES THE UNIVERSITY OF NEWCASTLE RESEARCH ASSOCIATES LIMITED (AU) 1999-07-29 WO claimed
US-4826888-A STORAGE STABLE, DISCOLORATION INHIBITION MITSUBISHI RAYON CO., LTD. (JP) 1989-05-02 US claimed
US-12503636-B2 Corrosion inhibitor composition for wet sour crude KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2025-12-23 US disclosed
US-20250345441-A1 ANTICANCER DRUGS AND METHODS OF MAKING AND USING SAME UNIV YALE (US) 2025-11-13 US disclosed
US-20250314585-A1 LOCALISED SURFACE PLASMONIC SENSING THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW (GB) 2025-10-09 US disclosed
US-20250276067-A1 ANTICANCER DRUGS AND METHODS OF MAKING AND USING SAME UNIV YALE (US) 2025-09-04 US disclosed
US-12338434-B1 Methods and materials for discovery of functional ligands to molecular complexes Base Pair Biotechnologies, Inc. (US) 2025-06-24 US disclosed
US-4415652-A ALKENYLAMINE-MODIFIED MALEIC ANHYDRIDE COPOLYMER, A MERCAPTO-CONTAINING CARBOXYLIC ACID AND PHOTOINITIATOR; LITHOGRAPHY E. I. DU PONT DE NEMOURS & CO. (US) 1983-11-15 US disclosed
US-4415651-A UNSATURATED ADDITION POLYMER, A MERCAPTO-CONTAINING CARBOXYLIC ACID AND A PHOTOINITIATORS; LITHOGRAPHY E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-11-15 US disclosed
EP-0062474-A1 Photosensitive compositions containing a polyene E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-10-13 EP disclosed
US-4324744-A PHOTOINITIATORS BASF AKTIENGESELLSCHAFT (DE) 1982-04-13 US disclosed
US-4322214-A USING A SULFUR OR SULFURIZED VAT DYE IN AN ALKALINE BATH CONTAINING A MERCAPTO COMPOUND AND A SULFITE SALT; LEVELING ASAHI CHEMICAL COMPANY LIMITED (JP) 1982-03-30 US disclosed
US-4265723-A UNSATURATED POLYESTERS OR VINYL ESTERS OF POLYEPOXIDES AND A UV SENSITIZER OF AN ACYL PHOSPHINE OXIDE BASF AKTIENGESELLSCHAFT (DE) 1981-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250345441-A1 ANTICANCER DRUGS AND METHODS OF MAKING AND USING SAME MTHFD1, DHFR, ABCG2 ALDH1A1 469/4885TSHR 4534/4885TP53 8/4885
US-20250276067-A1 ANTICANCER DRUGS AND METHODS OF MAKING AND USING SAME MTHFD1, DHFR, ABCG2 ALDH1A1 469/4885TSHR 4534/4885TP53 8/4885
US-20070197577-A1 Inhibitors of anthrax lethal factor APAF1, ANTXR2, LITAF ALDH1A1 4059/4885TSHR 4478/4885TP53 1549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.