Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25410688 | 0.84 | EGFR (0.40) | EGFRKCNH2POLBMAPTMAPK1 | |
| SCHEMBL702504 | 0.81 | NPSR1 (0.47) | EGFRKCNH2POLBMAPTMAPK1 | |
| SCHEMBL9448847 | 0.78 | MAPT (0.43) | EGFRKCNH2POLBMAPTMAPK1 | |
| SCHEMBL339745 | 0.77 | TSHR (0.54) | EGFRKCNH2POLBMAPTMAPK1 | |
| SCHEMBL8543357 | 0.76 | HTT (0.58) | MAPTCCNT1CDK9HTTL3MBTL1 | |
| SCHEMBL916350 | 0.75 | CCNT1 (0.43) | EGFRKCNH2POLBMAPTMAPK1 | |
| SCHEMBL12212067 | 0.75 | NPSR1 (0.42) | EGFRKCNH2POLBMAPTMAPK1 | |
| SCHEMBL9849219 | 0.73 | NPSR1 (0.41) | EGFRKCNH2POLBMAPTMAPK1 | |
| SCHEMBL4538982 | 0.73 | KCNH2 (0.43) | EGFRKCNH2POLBMAPK1NPSR1 | |
| SCHEMBL901666 | 0.73 | HSD17B10 (0.41) | EGFRKCNH2NPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018539-A1 | DENDRITIC POLYMER AND ELECTRONIC DEVICE ELEMENT EMPLOYING THE POLYMER | SHARP KABUSHIKI KAISHA (JP) | 2004-03-04 | — | — | WO | disclosed |