Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25410688 | 0.83 | EGFR (0.40) | MAPTMAPK1POLBEGFRNPSR1 | |
| SCHEMBL10348806 | 0.82 | KMT2A (0.45) | MAPTMAPK1POLBEGFRNPSR1 | |
| SCHEMBL702504 | 0.81 | NPSR1 (0.47) | MAPTMAPK1POLBEGFRNPSR1 | |
| SCHEMBL5035394 | 0.80 | ACP3 (0.45) | MAPK1PTGS2PTGS1CXCL8MMP1 | |
| SCHEMBL5112475 | 0.78 | PTGS2 (0.46) | MAPTMAPK1POLBPTGS2PTGS1 | |
| SCHEMBL5983552 | 0.78 | PTGS2 (0.46) | MAPTMAPK1POLBPTGS2PTGS1 | |
| SCHEMBL30222272 | 0.78 | PTGS2 (0.46) | MAPTMAPK1POLBPTGS2PTGS1 | |
| SCHEMBL6659343 | 0.78 | EGFR (0.41) | MAPTMAPK1POLBEGFRHTT | |
| SCHEMBL9445932 | 0.77 | NPSR1 (0.41) | MAPTMAPK1POLBEGFRNPSR1 | |
| SCHEMBL915187 | 0.76 | FOLH1 (0.45) | MAPTMAPK1POLBHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5242908-A | Of dna and rna | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-07 | — | — | US | disclosed |