Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL702504 | 0.87 | NPSR1 (0.47) | NPSR1KCNH2EGFRTSHRMAPT | |
| SCHEMBL12212067 | 0.80 | NPSR1 (0.42) | NPSR1KCNH2EGFRTSHRMAPT | |
| SCHEMBL916350 | 0.80 | CCNT1 (0.43) | NPSR1KCNH2EGFRTSHRMAPT | |
| SCHEMBL339745 | 0.79 | TSHR (0.54) | NPSR1KCNH2EGFRTSHRMAPT | |
| SCHEMBL2008228 | 0.79 | NPSR1 (0.41) | NPSR1KCNH2EGFRTSHRMAPT | |
| SCHEMBL331041 | 0.79 | FDPS (0.41) | NPSR1KCNH2EGFRTSHRMAPT | |
| SCHEMBL901666 | 0.79 | HSD17B10 (0.41) | NPSR1KCNH2EGFRTSHR | |
| SCHEMBL9445932 | 0.79 | NPSR1 (0.41) | NPSR1KCNH2EGFRTSHRMAPT | |
| SCHEMBL4538982 | 0.79 | KCNH2 (0.43) | NPSR1KCNH2EGFRTSHRPOLB | |
| SCHEMBL26083263 | 0.79 | NPSR1 (0.44) | NPSR1KCNH2EGFRTSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421436-A2 | Substituted carboxytetrahydroisoquinolines and derivatives thereof having pharmaceutical activity | WARNER-LAMBERT COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |