Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6659548 | 1.00 | LMNA (0.47) | LMNAPOLBPKMCA12CA1 | |
| SCHEMBL31319539 | 0.85 | LMNA (0.48) | LMNAPOLBPKMCA12CA1 | |
| SCHEMBL490307 | 0.83 | PKM (0.48) | LMNAPOLBPKMCA12CA1 | |
| SCHEMBL9381287 | 0.82 | CA12 (0.52) | LMNAPOLBCA12CA1CA2 | |
| SCHEMBL29191471 | 0.80 | TSHR (0.51) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL11135068 | 0.79 | BLM (0.67) | LMNAPKMCA12CA1CA2 | |
| SCHEMBL669094 | 0.79 | LMNA (0.55) | LMNAPKMCA12CA1CA2 | |
| SCHEMBL11135072 | 0.79 | BLM (0.67) | LMNAPKMCA12CA1CA2 | |
| SCHEMBL491022 | 0.75 | LDHA (0.47) | LMNAPOLBPKMCA12CA1 | |
| SCHEMBL15241060 | 0.74 | CYP3A4 (0.49) | LMNAPKMCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004012506-A2 | ANTIMICROBIAL COMPOUNDS | EXEGENICS, INC. (US) | 2004-02-12 | — | — | WO | disclosed |