SCHEMBL6659680

SCHEMBL6659680

c1ccc(C2NCc3ccccc32)nc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPM5 Q9NZQ8 1/20 0.41
RECQL P46063 1/20 0.39
DDB1 Q16531 1/20 0.37
CRBN Q96SW2 1/20 0.37
KMT2A Q03164 2/20 0.37
NPC1 O15118 1/20 0.37
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.37
RAB9A P51151 1/20 0.37
CHRNB2 P17787 1/20 0.37
CHRNA4 P43681 1/20 0.37
DRD1 P21728 4/20 0.36
DRD2 P14416 3/20 0.36
DRD4 P21917 3/20 0.36
ADRA2A P08913 1/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36
DRD5 P21918 1/20 0.36
DRD3 P35462 1/20 0.36
PRCP P42785 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7698338 0.83 RECQL (0.59) RECQLKMT2AMAPTPRCPLMNA
SCHEMBL7702387 0.83 RECQL (0.59) RECQLKMT2AMAPTPRCPLMNA
SCHEMBL5023257 0.83 RECQL (0.59) RECQLKMT2AMAPTPRCPLMNA
SCHEMBL23356541 0.79 RECQL (0.35) RECQLKMT2ANPC1ALDH1A1MAPT
SCHEMBL1471226 0.72 ADRA1A (0.56) RECQLADRA2A
SCHEMBL27741885 0.72 DRD1 (0.38) RECQLKMT2AALDH1A1MAPTCHRNB2
SCHEMBL13727505 0.71 SMN1; SMN2 (0.63) KMT2AALDH1A1KDM4ELMNAMEN1
SCHEMBL1471223 0.71 DRD1 (0.37) RECQLKMT2AALDH1A1MAPTCHRNB2
SCHEMBL6985456 0.71 PRCP (0.66) RECQLKMT2ADRD1DRD2PRCP
SCHEMBL4365122 0.70 PRCP (0.42) KMT2ANPC1MAPTRAB9APRCP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0036388-B1 ISOINDOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1984-02-15 EP claimed
US-4367333-A PLASTICS CIBA-GEIGY CORPORATION (US) 1983-01-04 US claimed
EP-0020302-B1 NICKEL COMPLEX OF AN ISOINDOLINAZINE, ITS PREPARATION PROCESS, ITS USE FOR PIGMENTING HIGH MOLECULAR ORGANIC MATERIAL AND THIS HIGH MOLECULAR ORGANIC MATERIAL CIBA-GEIGY AG (CH) 1982-08-25 EP claimed
EP-0037372-A1 1:1-Nickel complexes of isoindoline azine, process for their preparation and their use CIBA-GEIGY AG (CH) 1981-10-07 EP claimed
EP-0036388-A2 Isoindoline derivatives, process for their preparation and their use CIBA-GEIGY AG (CH) 1981-09-23 EP claimed
EP-0036389-A2 Metal complexes of isoindoline azines, process for their preparation and their use CIBA-GEIGY AG (CH) 1981-09-23 EP claimed
EP-1004633-B1 Process for conditioning organic pigments SUN CHEMICAL CORP (US) 2004-08-11 EP disclosed
EP-1004633-A2 Process for conditioning organic pigments Bayer Corporation (US) 2000-05-31 EP disclosed
US-6013126-A Process for conditioning organic pigments BAYER CORPORATION (US) 2000-01-11 US disclosed
US-4970248-A Gamma modification of an azine pigment CIBA-GEIGY CORPORATION (US) 1990-11-13 US disclosed
US-4474952-A ORGANIC PIGMENTS CIBA-GEIGY CORPORATION (US) 1984-10-02 US disclosed
EP-0036388-B1 ISOINDOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1984-02-15 EP disclosed
EP-0036834-B1 PROCESS FOR THE PREPARATION OF METAL COMPLEXES OF ISOINDOLINE AZINES CIBA-GEIGY AG (CH) 1983-12-07 EP disclosed
EP-0036835-A1 Process for the preparation of metal complexes of isoindoline azines CIBA-GEIGY AG (CH) 1981-09-30 EP disclosed
EP-0036834-A1 Process for the preparation of metal complexes of isoindoline azines CIBA-GEIGY AG (CH) 1981-09-30 EP disclosed
EP-0036836-A2 Metal complexes of isoindoline azines, processes for their preparation and their use CIBA-GEIGY AG (CH) 1981-09-30 EP disclosed
EP-0036388-A2 Isoindoline derivatives, process for their preparation and their use CIBA-GEIGY AG (CH) 1981-09-23 EP disclosed
EP-0036389-A2 Metal complexes of isoindoline azines, process for their preparation and their use CIBA-GEIGY AG (CH) 1981-09-23 EP disclosed
EP-0036389-A2 Metal complexes of isoindoline azines, process for their preparation and their use CIBA-GEIGY AG (CH) 1981-09-23 EP disclosed
EP-0020302-A1 Nickel complex of an isoindolinazine, its preparation process, its use for pigmenting high molecular organic material and this high molecular organic material CIBA-GEIGY AG (CH) 1980-12-10 EP disclosed