Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6659789 | 1.00 | RAB9A (0.44) | RAB9AALDH1A1SMN1; SMN2TSHRNPC1 | |
| SCHEMBL30189346 | 0.83 | TSHR (0.49) | RAB9AALDH1A1SMN1; SMN2TSHRNPC1 | |
| SCHEMBL6663445 | 0.81 | CTSD (0.56) | RAB9AALDH1A1SMN1; SMN2TSHRNPC1 | |
| SCHEMBL6663448 | 0.81 | CTSD (0.56) | RAB9AALDH1A1SMN1; SMN2TSHRNPC1 | |
| SCHEMBL17755154 | 0.81 | TSHR (0.53) | RAB9AALDH1A1SMN1; SMN2TSHRNPC1 | |
| SCHEMBL10353055 | 0.79 | TSHR (0.48) | RAB9AALDH1A1SMN1; SMN2TSHRNPC1 | |
| SCHEMBL7921709 | 0.77 | TSHR (0.50) | RAB9AALDH1A1SMN1; SMN2TSHRNPC1 | |
| SCHEMBL1143781 | 0.77 | TSHR (0.50) | RAB9AALDH1A1SMN1; SMN2TSHRNPC1 | |
| SCHEMBL1143779 | 0.77 | TSHR (0.50) | RAB9AALDH1A1SMN1; SMN2TSHRNPC1 | |
| SCHEMBL14588760 | 0.76 | TSHR (0.48) | RAB9AALDH1A1SMN1; SMN2TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004011414-A1 | E-ISOMERIC β-AROMATIC OR HETEROAROMATIC SUBSTITUTED β-ACYLAMINO-ACRYLATES AND METHODS OF PREPARING THE SAME | DSM IP ASSETS B.V. (NL) | 2004-02-05 | — | — | WO | disclosed |