Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.42 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1143781 | 1.00 | TSHR (0.50) | TSHRMAPTHSD17B10PARP1POLB | |
| SCHEMBL1143779 | 1.00 | TSHR (0.50) | TSHRMAPTHSD17B10PARP1POLB | |
| 1,2-Dimethoxybenzene SCHEMBL28244366 | 0.93 | PDE4A (0.48) | TSHRMAPTPOLBRAB9AALDH1A1 | |
| SCHEMBL6657569 | 0.83 | TDP1 (0.52) | MAPTHSD17B10TDP1RAB9AMAPK1 | |
| SCHEMBL6657574 | 0.83 | TDP1 (0.52) | MAPTHSD17B10TDP1RAB9AMAPK1 | |
| SCHEMBL7931264 | 0.81 | RAB9A (0.45) | TSHRMAPTHSD17B10CYP2C19L3MBTL1 | |
| SCHEMBL14691237 | 0.81 | SMN1; SMN2 (0.59) | TSHRMAPTHSD17B10CYP2C19RAB9A | |
| SCHEMBL2649166 | 0.81 | SMN1; SMN2 (0.59) | TSHRMAPTHSD17B10CYP2C19RAB9A | |
| SCHEMBL7931260 | 0.81 | RAB9A (0.45) | TSHRMAPTHSD17B10CYP2C19L3MBTL1 | |
| SCHEMBL7933746 | 0.81 | RAB9A (0.66) | HSD17B10PARP1CYP3A4CYP2C19RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104326966-B | The method of diaminoalkenes hydrocarbon derivative is replaced by the synthesis of C-N oxidative coupling | TIANJIN UNIVERSITY (CN) | 2016-03-30 | — | — | CN | disclosed |
| CN-104326966-A | Method for synthesizing substituted diamino olefin derivative through C-N oxidative coupling | UNIV TIANJIN | 2015-02-04 | — | — | CN | disclosed |
| US-7495123-B2 | Process for the preparation of enantiomerically enriched beta amino acid derivatives | SOLVIAS AG (CH) | 2009-02-24 | — | — | US | disclosed |
| US-7495123-B2 | Process for the preparation of enantiomerically enriched beta amino acid derivatives | SOLVIAS AG (CH) | 2009-02-24 | — | — | US | disclosed |
| US-20080058522-A1 | Process For The Preparation Of Enantiomerically Enriched Beta Amino Acid Derivatives | MERCK SHARP & DOHME LLC | 2008-03-06 | — | — | US | disclosed |
| US-20080058522-A1 | Process For The Preparation Of Enantiomerically Enriched Beta Amino Acid Derivatives | MERCK SHARP & DOHME LLC | 2008-03-06 | — | — | US | disclosed |
| US-6239074-B1 | HERBICIDES, INSECTICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2001-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058522-A1 | Process For The Preparation Of Enantiomerically Enriched Beta Amino Acid Derivatives | ATIC, SLC1A5, SLC7A1 | TSHR 1429/4885MAPT 4363/4885HSD17B10 4212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.