SCHEMBL6659932

SCHEMBL6659932

CCOc1cc2nc(C)sc2cc1C

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.59
SMN1; SMN2 Q16637 5/20 0.53
HSD17B10 Q99714 4/20 0.53
TP53 P04637 4/20 0.53
ALDH1A1 P00352 4/20 0.53
NPC1 O15118 4/20 0.53
RAB9A P51151 4/20 0.53
MAPT P10636 2/20 0.53
PKM P14618 1/20 0.53
HPGD P15428 1/20 0.53
ALOX15 P16050 1/20 0.49
ATM Q13315 1/20 0.49
MAPK1 P28482 2/20 0.49
KDM4E B2RXH2 1/20 0.49
CYP3A4 P08684 2/20 0.40
TSHR P16473 2/20 0.40
RXFP1 Q9HBX9 1/20 0.39
LMNA P02545 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18618286 0.81 ALOX15 (0.66) GAASMN1; SMN2HSD17B10TP53ALDH1A1
SCHEMBL33272 0.76 GAA (1.00) GAASMN1; SMN2HSD17B10TP53ALDH1A1
SCHEMBL21983966 0.75 GAA (0.58) GAASMN1; SMN2HSD17B10TP53ALDH1A1
SCHEMBL6760635 0.75 PTK6 (0.41) SMN1; SMN2HSD17B10ALDH1A1NPC1RAB9A
Bromide SCHEMBL10995945 0.74 GAA (0.95) GAASMN1; SMN2HSD17B10TP53ALDH1A1
SCHEMBL9310828 0.74 GAA (0.66) GAASMN1; SMN2HSD17B10TP53ALDH1A1
SCHEMBL14318920 0.73 HSD17B10 (0.53) GAASMN1; SMN2HSD17B10TP53ALDH1A1
SCHEMBL8244075 0.73 PDE10A (0.59) GAASMN1; SMN2HSD17B10TP53ALDH1A1
SCHEMBL31487019 0.73 PDE10A (0.59) GAASMN1; SMN2HSD17B10TP53ALDH1A1
SCHEMBL8261943 0.73 KMT2A (0.69) GAASMN1; SMN2HSD17B10TP53ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004010761-A2 PESTICIDAL CYANINE DYE DERIVATIVES FMC CORPORATION (US) 2004-02-05 WO disclosed
US-4237214-A P-DIHYDROXYBENZENE DEVELOPING AGENT FUJI PHOTO FILM CO., LTD. (JP) 1980-12-02 US disclosed