SCHEMBL6760635

SCHEMBL6760635

CCOc1cc2ncsc2cc1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTK6 Q13882 1/20 0.41
ALDH1A1 P00352 5/20 0.40
PKM P14618 1/20 0.40
KDM4E B2RXH2 4/20 0.36
HSD17B10 Q99714 3/20 0.36
MAPK1 P28482 2/20 0.36
DRD2 P14416 1/20 0.35
SMN1; SMN2 Q16637 4/20 0.34
TDP1 Q9NUW8 3/20 0.34
NPC1 O15118 3/20 0.34
RAB9A P51151 3/20 0.34
HTT P42858 2/20 0.34
HPGD P15428 1/20 0.34
CASP1 P29466 1/20 0.34
CASP7 P55210 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
POLB P06746 1/20 0.33
TAS1R3 Q7RTX0 1/20 0.33
TAS1R1 Q7RTX1 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9440631 0.93 PTK6 (0.41) PTK6ALDH1A1PKMKDM4EHSD17B10
SCHEMBL11121899 0.87 PTK6 (0.43) PTK6ALDH1A1PKMKDM4EHSD17B10
SCHEMBL5080801 0.82 PTK6 (0.39) PTK6ALDH1A1PKMKDM4EHSD17B10
SCHEMBL6312070 0.78 PTK6 (0.45) PTK6ALDH1A1PKMKDM4EHSD17B10
SCHEMBL4048510 0.77 GAA (0.45) ALDH1A1KDM4EHSD17B10MAPK1SMN1; SMN2
SCHEMBL9117566 0.75 P2RX7 (0.40) PTK6ALDH1A1PKMKDM4EHSD17B10
SCHEMBL6659932 0.75 GAA (0.59) ALDH1A1PKMKDM4EHSD17B10MAPK1
SCHEMBL8980355 0.73 TSHR (0.49) PTK6ALDH1A1PKMKDM4EHSD17B10
SCHEMBL11795684 0.72 ALDH1A1 (0.45) PTK6ALDH1A1PKMKDM4EHSD17B10
SCHEMBL6032512 0.72 DRD2 (0.44) PTK6ALDH1A1PKMKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5861424-A CATIONIC HETEROCYCLIC COMPOUNDS FOR TREATING CANCER DANA FARBER CANCER INSTITUTE (US) 1999-01-19 US claimed
CN-100370358-C Silver halide photographic light sensitive material FUJI PHOTO FILM CO LTD (JP) 2008-02-20 CN disclosed
US-6828088-B2 Contrast and sensitivity FUJI PHOTO FILM CO., LTD. (JP) 2004-12-07 US disclosed
CN-1521561-A Silver halide photographic light sensitive material 富士胶片株式会社 2004-08-18 CN disclosed
US-20040048207-A1 Silver halide photographic light-sensitive material FUJIFILM CORPORATION (JP) 2004-03-11 US disclosed
EP-1315031-A2 Silver halide photographic light-sensitive material Fuji Photo Film Co. Ltd. (JP) 2003-05-28 EP disclosed
EP-1111451-A2 Photothermographic material FUJI PHOTO FILM CO., LTD. (JP) 2001-06-27 EP disclosed
US-6245499-B1 PHOTOSENSITIVE LAYER(S) COMPRISING AN ORGANIC SILVER SALT, A SILVER HALIDE, A REDUCING AGENT, A HYDRAZINE DERIVATIVE AND A SENSITIZING DYE; HIGH DMAX, HIGH CONTRAST, COLOR RESOLUTION, IMAGE QUALITY, PRINTING PLATES FUJI PHOTO FILM CO., LTD. (JP) 2001-06-12 US disclosed
EP-0514675-B1 Silver halide photographic materials and method for processing the same FUJI PHOTO FILM CO LTD (JP) 1999-12-08 EP disclosed
US-5942384-A SUPPORT HAVING A LIGHT SENSITIVE SILVER HALIDE EMULSION LAYER CONTAINING A SPECIFIC MOLE % OF SELENIUM-SENSITIZED AND SULFUR SENSITIZED SILVER HALIDE GRAINS, AND A RHODIUM COMPOUND; RAPID PROCESSING FUJI PHOTO FILM CO., LTD. (JP) 1999-08-24 US disclosed
EP-0395388-A2 Image forming method KONICA CORPORATION (JP) 1990-10-31 EP disclosed
US-4945036-A LASER BEAM EXPOSURE FUJI PHOTO FILM CO., LTD. (JP) 1990-07-31 US disclosed
EP-0367243-A1 A silver halide photographic light-sensitive material excellent in antistatic property KONICA CORPORATION (JP) 1990-05-09 EP disclosed
US-4780399-A SENSITIZING-DYE HAVING OXAZOLE, THIAZOLE, IMIDAZOLE RINGS OR BENZO-AND NAPHTHO-COMPLETING DERIVATIVES FUJI PHOTO FILM CO., LTD. (JP) 1988-10-25 US disclosed
EP-0105425-B1 SILVER HALIDE PHOTOGRAPHIC LIGHT SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1987-05-27 EP disclosed
US-4609621-A REDUCED DEPENDENCE ON DEVELOPMENT PROCESSING CONDITIONS FUJI PHOTO FILM CO., LTD. (JP) 1986-09-02 US disclosed
EP-0105425-A2 Silver halide photographic light sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1984-04-18 EP disclosed
US-4308345-A CYANINE DYES FOR COLOR FUJI PHOTO FILM CO., LTD. (JP) 1981-12-29 US disclosed
US-4307185-A SENSITIZING DYE OF CYANINE STRUCTURE FUJI PHOTO FILM CO., LTD. (JP) 1981-12-22 US disclosed
US-4212672-A CYANINE SENSITIZER DYE, SULFONIC ACID-SUBSTITUTED HETEROCYCLIC COMPOUND, POLYOXYALKYLENE OXIDE FUJI PHOTO FILM CO., LTD. (JP) 1980-07-15 US disclosed