Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6659197 | 0.88 | MAPT (0.54) | GAADRD2DRD4DRD3KMT2A | |
| SCHEMBL6656984 | 0.88 | MEN1 (0.51) | HTR6GAADRD2DRD4DRD3 | |
| SCHEMBL6656820 | 0.85 | DRD2 (0.54) | DRD2DRD4DRD3KMT2AMEN1 | |
| SCHEMBL6658888 | 0.83 | MAPT (0.61) | GAAKMT2AMEN1MAPTLMNA | |
| SCHEMBL6661644 | 0.82 | DRD2 (0.50) | DRD2DRD4DRD3KMT2AMEN1 | |
| SCHEMBL6658613 | 0.81 | PPARG (0.46) | KDM4EDRD2DRD4DRD3KMT2A | |
| SCHEMBL6657196 | 0.81 | MEN1 (0.57) | KDM4EKMT2AMEN1MAPTLMNA | |
| SCHEMBL6658791 | 0.81 | KCNH2 (0.46) | GAAKMT2AMEN1MAPTLMNA | |
| SCHEMBL6660405 | 0.81 | KCNH2 (0.45) | GAAKMT2AMEN1MAPTLMNA | |
| SCHEMBL6662210 | 0.80 | MAPT (0.56) | KDM4EDRD2DRD4DRD3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004004715-A2 | NOVEL DELTA OPIOID RECEPTOR LIGANDS | GLAXOSMITHKLINE SPA (IT) | 2004-01-15 | — | — | WO | disclosed |