Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6658791 | 0.91 | KCNH2 (0.46) | KCNH2KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL6656984 | 0.85 | MEN1 (0.51) | KMT2AMAPTMEN1ALDH1A1LMNA | |
| SCHEMBL6659197 | 0.83 | MAPT (0.54) | KCNH2KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL6656115 | 0.83 | KCNH2 (0.41) | KCNH2KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL6656820 | 0.81 | DRD2 (0.54) | KMT2AMAPTMEN1ALDH1A1LMNA | |
| SCHEMBL6658888 | 0.81 | MAPT (0.61) | KMT2AMAPTMEN1ALDH1A1LMNA | |
| SCHEMBL6660181 | 0.81 | HTR6 (0.46) | KCNH2KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL6657196 | 0.79 | MEN1 (0.57) | KMT2AMAPTMEN1ALDH1A1LMNA | |
| SCHEMBL6661644 | 0.78 | DRD2 (0.50) | KMT2AMAPTMEN1ALDH1A1LMNA | |
| SCHEMBL6658613 | 0.77 | PPARG (0.46) | KMT2AMAPTMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004004715-A2 | NOVEL DELTA OPIOID RECEPTOR LIGANDS | GLAXOSMITHKLINE SPA (IT) | 2004-01-15 | — | — | WO | disclosed |