SCHEMBL6660767

SCHEMBL6660767

CCCc1ccc(COC(F)(F)Cc2ccc(C(F)(F)F)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.47
TAAR1 Q96RJ0 1/20 0.44
MAOB P27338 6/20 0.44
KMT2A Q03164 1/20 0.41
MIF P14174 1/20 0.38
PTPN1 P18031 1/20 0.38
DAO P14920 1/20 0.37
PSMB5 P28074 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6661132 0.92 LPL (0.38) PTPN1
SCHEMBL6661860 0.89 ESR1 (0.44) IDO1TAAR1MAOB
SCHEMBL6666035 0.87 TAAR1 (0.38) TAAR1PTPN1
SCHEMBL6662034 0.87 IDO1 (0.50) IDO1TAAR1MAOBKMT2APTPN1
SCHEMBL6661146 0.85 ALDH1A1 (0.42) IDO1TAAR1MAOBKMT2A
SCHEMBL6661972 0.84 ESR1 (0.47)
SCHEMBL6662752 0.84 ESR1 (0.47)
SCHEMBL1696674 0.82 TAAR1 (0.61) IDO1TAAR1MAOBMIFDAO
SCHEMBL6666711 0.81 TSHR (0.42) DAO
Ammonia Solution, Strong SCHEMBL6193177 0.80 TAAR1 (0.59) IDO1TAAR1MAOBMIFDAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0893423-B1 LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES CHISSO CORP (JP) 2004-09-01 EP disclosed