SCHEMBL6666035

SCHEMBL6666035

CCCc1ccc(CC(F)(F)OCc2ccc(CC)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.38
PTPN1 P18031 1/20 0.36
LPL P06858 1/20 0.35
LIPG Q9Y5X9 1/20 0.35
FAAH O00519 1/20 0.34
GPR84 Q9NQS5 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.33
CA2 P00918 1/20 0.33
THRB P10828 1/20 0.33
NR2F2 P24468 1/20 0.32
PAX8 Q06710 1/20 0.32
KLF5 Q13887 1/20 0.32
NPC1 O15118 1/20 0.32
MAPT P10636 1/20 0.32
CASP3 P42574 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
SENP8 Q96LD8 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6661132 0.95 LPL (0.38) PTPN1LPLLIPGFAAHGPR84
SCHEMBL6666978 0.89 FAAH (0.48) LPLLIPGFAAHCA2KDM4E
SCHEMBL6661146 0.88 ALDH1A1 (0.42) TAAR1L3MBTL1ALDH1A1GAA
SCHEMBL6666711 0.87 TSHR (0.42) GPR84THRBALDH1A1
SCHEMBL6661972 0.87 ESR1 (0.47) LPLLIPGFAAHCA2KDM4E
SCHEMBL6662752 0.87 ESR1 (0.47) LPLLIPGFAAHCA2KDM4E
SCHEMBL6660767 0.87 IDO1 (0.47) TAAR1PTPN1
SCHEMBL6667004 0.84 LMNA (0.47) PTPN1L3MBTL1NPC1MAPTRAB9A
SCHEMBL6665297 0.83 TSHR (0.44) L3MBTL1NPC1RAB9ASMN1; SMN2KDM4E
SCHEMBL6662961 0.83 ESR1 (0.50) LPLLIPGFAAHCA2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0893423-B1 LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES CHISSO CORP (JP) 2004-09-01 EP disclosed