SCHEMBL6660880

SCHEMBL6660880

OCCOCCOCCNCc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DRD4 P21917 4/20 0.56
KDM4E B2RXH2 3/20 0.56
LMNA P02545 2/20 0.56
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
TDP1 Q9NUW8 2/20 0.55
DRD2 P14416 2/20 0.53
DRD3 P35462 2/20 0.53
GAA P10253 2/20 0.52
ALDH1A1 P00352 2/20 0.52
MAPK1 P28482 1/20 0.52
HTT P42858 1/20 0.52
MAOA P21397 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
ADRA1D P25100 1/20 0.49
ADRA1A P35348 1/20 0.49
ADRA1B P35368 1/20 0.49
CHRM2 P08172 1/20 0.48
MAPT P10636 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4406338 0.98 DRD4 (0.58) DRD4KDM4ELMNAMEN1KMT2A
SCHEMBL893830 0.91 TDP1 (0.67) DRD4KDM4ELMNAMEN1KMT2A
SCHEMBL11179375 0.91 TDP1 (0.67) DRD4KDM4ELMNAMEN1KMT2A
SCHEMBL1625040 0.89 ALDH1A1 (0.49) DRD4KDM4ELMNAMEN1KMT2A
SCHEMBL4591762 0.84 CYP1A2 (0.47) KDM4ELMNAMEN1KMT2ATDP1
SCHEMBL2592983 0.84 SMN1; SMN2 (0.49) KDM4ELMNAALDH1A1HTTSMN1; SMN2
SCHEMBL21657638 0.82 DRD4 (0.56) DRD4KDM4ELMNAMEN1KMT2A
SCHEMBL21657446 0.82 KDM4E (0.59) DRD4KDM4ELMNAMEN1KMT2A
SCHEMBL7480733 0.82 DRD4 (0.56) DRD4KDM4ELMNAMEN1KMT2A
SCHEMBL25242339 0.82 BCHE (0.65) DRD4KDM4EMEN1KMT2ADRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113731406-B Method for improving palladium carbon activity hydrogenation removal protecting group 南京工业大学 2023-07-28 CN disclosed
CN-113731406-A Method for improving palladium-carbon activity and removing protective group by hydrogenation 南京工业大学 2021-12-03 CN disclosed
EP-1082138-B1 TEXAPHYRIN CONJUGATES AND USES THEREOF UNIV TEXAS (US) 2004-08-25 EP disclosed
US-6207660-B1 Texaphyrin conjugates and uses thereof PHARMACYCLICS, INC. 2001-03-27 US disclosed
EP-1082138-A1 TEXAPHYRIN CONJUGATES AND USES THEREOF THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2001-03-14 EP disclosed
WO-1999062551-A1 TEXAPHYRIN CONJUGATES AND USES THEREOF BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1999-12-09 WO disclosed