Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 5/20 | 0.47 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3586824 | 0.86 | SPHK2 (0.58) | ATMSPHK2SPHK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6659601 | 0.81 | ATM (0.61) | ATMSMN1; SMN2ALDH1A1HTTL3MBTL1 | |
| SCHEMBL6664749 | 0.79 | LMNA (0.63) | ATMSMN1; SMN2ALDH1A1HTTL3MBTL1 | |
| SCHEMBL6657326 | 0.78 | HDAC2 (0.65) | SMN1; SMN2ALDH1A1HDAC1HDAC8HDAC6 | |
| SCHEMBL17061417 | 0.77 | BRD4 (0.56) | BRD4SLC6A5SMN1; SMN2MTNR1BKMT2A | |
| SCHEMBL28236202 | 0.77 | KDM4E (0.53) | ATMSMN1; SMN2SMPD1HDAC1HDAC8 | |
| SCHEMBL16015328 | 0.74 | MAPT (0.57) | SLC6A5SMN1; SMN2ALDH1A1PTGESSMPD1 | |
| SCHEMBL3605042 | 0.73 | HDAC3 (0.46) | SPHK2SPHK1SMN1; SMN2ALDH1A1HDAC1 | |
| SCHEMBL11757864 | 0.72 | KMT2A (0.67) | BRD4SMN1; SMN2MTNR1BSMPD1HDAC1 | |
| SCHEMBL18644999 | 0.72 | SGMS2 (0.72) | ALDH1A1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888389-B1 | PHOTOACTIVATABLE CHAIN TRANSFER AGENTS | SURMODICS INC (US) | 2004-08-04 | — | — | EP | disclosed |
| EP-0888389-A4 | PHOTOACTIVATABLE CHAIN TRANSFER AGENTS | SURMODICS INC (US) | 2001-03-14 | — | — | EP | disclosed |
| US-5942555-A | Photoactivatable chain transfer agents and semi-telechelic photoactivatable polymers prepared therefrom | SURMODICS, INC. (US) | 1999-08-24 | — | — | US | disclosed |
| EP-0888389-A1 | PHOTOACTIVATABLE CHAIN TRANSFER AGENTS | SurModics, Inc. (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997034935-A1 | PHOTOACTIVATABLE CHAIN TRANSFER AGENTS | BSI CORPORATION (US) | 1997-09-25 | — | — | WO | disclosed |