Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | CA1 | P00915 | 6/20 | 0.58 |
| ▸ | CA2 | P00918 | 6/20 | 0.58 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.58 |
| ▸ | PARP1 | P09874 | 1/20 | 0.58 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.58 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.58 |
| ▸ | PDE4A | P27815 | 1/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7933746 | 1.00 | RAB9A (0.66) | RAB9AMAPK1HSD17B10CA1CA2 | |
| SCHEMBL6661088 | 1.00 | RAB9A (0.66) | RAB9AMAPK1HSD17B10CA1CA2 | |
| SCHEMBL6657569 | 0.84 | TDP1 (0.52) | RAB9AMAPK1HSD17B10PDE4APDE4B | |
| SCHEMBL6657574 | 0.84 | TDP1 (0.52) | RAB9AMAPK1HSD17B10PDE4APDE4B | |
| SCHEMBL30189391 | 0.83 | MAPK1 (0.59) | RAB9AMAPK1HSD17B10CA1CA2 | |
| SCHEMBL28810859 | 0.83 | MAPK1 (0.59) | RAB9AMAPK1HSD17B10CA1CA2 | |
| SCHEMBL2649166 | 0.82 | SMN1; SMN2 (0.59) | RAB9AMAPK1HSD17B10CA1CA2 | |
| SCHEMBL14691237 | 0.82 | SMN1; SMN2 (0.59) | RAB9AMAPK1HSD17B10CA1CA2 | |
| SCHEMBL7931260 | 0.82 | RAB9A (0.45) | RAB9AMAPK1HSD17B10PDE4APDE4B | |
| SCHEMBL7931264 | 0.82 | RAB9A (0.45) | RAB9AMAPK1HSD17B10PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004011414-A1 | E-ISOMERIC β-AROMATIC OR HETEROAROMATIC SUBSTITUTED β-ACYLAMINO-ACRYLATES AND METHODS OF PREPARING THE SAME | DSM IP ASSETS B.V. (NL) | 2004-02-05 | — | — | WO | disclosed |