Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7931260 | 1.00 | RAB9A (0.45) | RAB9AMAPK1HSD17B10HPGDLMNA | |
| SCHEMBL6657569 | 0.84 | TDP1 (0.52) | RAB9AMAPK1HSD17B10HPGDLMNA | |
| SCHEMBL6657574 | 0.84 | TDP1 (0.52) | RAB9AMAPK1HSD17B10HPGDLMNA | |
| SCHEMBL6661088 | 0.82 | RAB9A (0.66) | RAB9AMAPK1HSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL6661082 | 0.82 | RAB9A (0.66) | RAB9AMAPK1HSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL14691237 | 0.82 | SMN1; SMN2 (0.59) | RAB9AMAPK1HSD17B10HPGDALDH1A1 | |
| SCHEMBL1928738 | 0.82 | SMN1; SMN2 (0.59) | RAB9AMAPK1HSD17B10HPGDALDH1A1 | |
| SCHEMBL7933746 | 0.82 | RAB9A (0.66) | RAB9AMAPK1HSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL2649166 | 0.82 | SMN1; SMN2 (0.59) | RAB9AMAPK1HSD17B10HPGDALDH1A1 | |
| SCHEMBL3521887 | 0.81 | PDE4A (0.49) | RAB9AHPGDLMNAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010031865-A1 | Substituted 3-phenyluracils | KLINTZ RALF (DE) | 2001-10-18 | — | — | US | disclosed |
| US-6239074-B1 | HERBICIDES, INSECTICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2001-05-29 | — | — | US | disclosed |
| US-4540791-A | FROM A NITRICE AND A HALO ESTER | CIBA-GEIGY CORPORATION (US) | 1985-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010031865-A1 | Substituted 3-phenyluracils | CCR1, CCR6, CCR3 | RAB9A 3028/4885MAPK1 3667/4885HSD17B10 1401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.