Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 16/20 | 0.50 |
| ▸ | DHFR | P00374 | 1/20 | 0.48 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.48 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6662145 | 0.83 | DHODH (0.56) | DHODH | |
| SCHEMBL6665622 | 0.78 | ESR1 (0.48) | DHODHDHFRALKBH5 | |
| SCHEMBL6661826 | 0.76 | ADORA2A (0.53) | DHODH | |
| SCHEMBL10580409 | 0.71 | DHODH (0.80) | DHODHDHFRALKBH5 | |
| SCHEMBL12111550 | 0.71 | PIK3R1 (0.56) | DHODHDHFRALKBH5PIK3R1PIK3CA | |
| SCHEMBL12111662 | 0.71 | PIK3R1 (0.56) | DHODHDHFRALKBH5PIK3R1PIK3CA | |
| SCHEMBL12111551 | 0.71 | PIK3R1 (0.56) | DHODHDHFRALKBH5PIK3R1PIK3CA | |
| SCHEMBL12111629 | 0.71 | PIK3R1 (0.56) | DHODHDHFRALKBH5PIK3R1PIK3CA | |
| SCHEMBL6662378 | 0.69 | DHODH (0.50) | DHODH | |
| SCHEMBL8956069 | 0.69 | LMNA (0.51) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861864-B1 | Method of preparation of polyquinolines | HITACHI CHEMICAL CO LTD (JP) | 2004-08-25 | — | — | EP | disclosed |
| EP-0861864-A2 | Method of preparation of polyquinolines | HITACHI CHEMICAL CO., LTD. (JP) | 1998-09-02 | — | — | EP | disclosed |
| US-5786071-A | Method of preparation of polyquinolines | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1998-07-28 | — | — | US | disclosed |
| US-5723573-A | ACETYLENIC END GROUPS | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1998-03-03 | — | — | US | disclosed |
| US-5648448-A | Method of preparation of polyquinolines | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1997-07-15 | — | — | US | disclosed |