Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6665297 | 0.88 | TSHR (0.44) | CYP2A6RAB9ALOXL2MAOBNPC1 | |
| SCHEMBL6666752 | 0.84 | HSD17B10 (0.58) | CYP2A6RAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL6667004 | 0.80 | LMNA (0.47) | RAB9AMAOBNPC1L3MBTL1GAA | |
| SCHEMBL6663198 | 0.80 | CYP2A6 (0.38) | CYP2A6RAB9AMAOBL3MBTL1MAOA | |
| SCHEMBL6662034 | 0.79 | IDO1 (0.50) | MAOBKMT2A | |
| SCHEMBL6666035 | 0.79 | TAAR1 (0.38) | RAB9ANPC1SMN1; SMN2L3MBTL1GAA | |
| SCHEMBL6665025 | 0.79 | TRPV4 (0.41) | CYP2A6MAOBMAOA | |
| SCHEMBL6666666 | 0.78 | MEN1 (0.43) | CYP2A6RAB9AMAOBMAOAGAA | |
| SCHEMBL6664949 | 0.78 | TSHR (0.45) | L3MBTL1TSHR | |
| SCHEMBL91062 | 0.77 | CYP2A6 (1.00) | CYP2A6LOXL2MAOBMAOATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893423-B1 | LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES | CHISSO CORP (JP) | 2004-09-01 | — | — | EP | disclosed |