Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 6/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 5/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5337976 | 1.00 | FPR1 (0.43) | FPR1IDH1FPR2UTS2RPKM | |
| SCHEMBL5334263 | 0.89 | IDH1 (0.44) | FPR1IDH1FPR2UTS2RCNR1 | |
| SCHEMBL5455229 | 0.85 | IDH1 (0.41) | FPR1IDH1FPR2UTS2RCNR1 | |
| SCHEMBL5220112 | 0.85 | FPR1 (0.41) | FPR1IDH1FPR2UTS2RCNR1 | |
| SCHEMBL5220717 | 0.84 | FPR1 (0.41) | FPR1IDH1FPR2UTS2RCNR1 | |
| SCHEMBL5220710 | 0.84 | FPR1 (0.41) | FPR1IDH1FPR2UTS2RCNR1 | |
| SCHEMBL5339131 | 0.83 | HSD17B1 (0.36) | FPR1FPR2UTS2RALDH1A1 | |
| SCHEMBL5333712 | 0.80 | MAPT (0.36) | FPR2 | |
| SCHEMBL5331514 | 0.79 | NTRK1 (0.42) | FPR2 | |
| SCHEMBL6636221 | 0.79 | EPHX2 (0.43) | LMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487435-A1 | AZETIDINE DERIVATIVES AS CCR-3 RECEPTOR ANTAGONISTS | Novartis AG (CH) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003077907-A1 | AZETIDINE DERIVATIVES AS CCR-3 RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2003-09-25 | — | — | WO | disclosed |