Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 4/20 | 0.43 |
| ▸ | FPR1 | P21462 | 4/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5337976 | 0.89 | FPR1 (0.43) | IDH1FPR2FPR1UTS2RCNR1 | |
| SCHEMBL6661476 | 0.89 | FPR1 (0.43) | IDH1FPR2FPR1UTS2RCNR1 | |
| SCHEMBL6620293 | 0.75 | CNR1 (0.49) | IDH1FPR2CNR1MAPK1LMNA | |
| SCHEMBL5455229 | 0.74 | IDH1 (0.41) | IDH1FPR2FPR1UTS2RCNR1 | |
| SCHEMBL5220112 | 0.74 | FPR1 (0.41) | IDH1FPR2FPR1UTS2RCNR1 | |
| SCHEMBL5339131 | 0.74 | HSD17B1 (0.36) | FPR2FPR1UTS2RALDH1A1 | |
| SCHEMBL5332924 | 0.73 | ACACB (0.36) | FPR2FPR1UTS2R | |
| SCHEMBL5332921 | 0.73 | ACACB (0.36) | FPR2FPR1UTS2R | |
| SCHEMBL5220710 | 0.72 | FPR1 (0.41) | IDH1FPR2FPR1UTS2RCNR1 | |
| SCHEMBL5220717 | 0.72 | FPR1 (0.41) | IDH1FPR2FPR1UTS2RCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7288537-B2 | Azetidine derivatives as CCR-3 receptor antagonists | NOVARTIS AG (CH) | 2007-10-30 | — | — | US | disclosed |
| US-20050222118-A1 | Azetidine derivatives as ccr-3 receptor antagonists | NOVARTIS AG (CH) | 2005-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222118-A1 | Azetidine derivatives as ccr-3 receptor antagonists | CCR3, CCR1, CCR9 | IDH1 3724/4885FPR2 132/4885FPR1 89/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.