Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 4/20 | 0.54 |
| ▸ | CTSL | P07711 | 3/20 | 0.54 |
| ▸ | CTSS | P25774 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 3/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP4 | P49662 | 1/20 | 0.50 |
| ▸ | CASP5 | P51878 | 1/20 | 0.50 |
| ▸ | CASP9 | P55211 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.50 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.48 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.48 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6666188 | 0.89 | CTSB (0.57) | CTSBCTSLCTSSMEN1KMT2A | |
| SCHEMBL6662946 | 0.88 | PSMB5 (0.55) | CTSBCTSLCTSSMEN1KMT2A | |
| SCHEMBL15462629 | 0.85 | CASP1 (0.56) | CTSBCTSLCTSSMEN1KMT2A | |
| SCHEMBL20052435 | 0.85 | CASP1 (0.56) | CTSBCTSLCTSSMEN1KMT2A | |
| SCHEMBL20052390 | 0.85 | CASP1 (0.56) | CTSBCTSLCTSSMEN1KMT2A | |
| SCHEMBL20052400 | 0.84 | MME (0.50) | CTSBCTSLCTSSMEN1KMT2A | |
| SCHEMBL15462622 | 0.84 | MME (0.50) | CTSBCTSLCTSSMEN1KMT2A | |
| SCHEMBL20356162 | 0.84 | MME (0.50) | CTSBCTSLCTSSMEN1KMT2A | |
| SCHEMBL13471247 | 0.84 | CASP3 (0.50) | CTSBCTSLCTSSMEN1KMT2A | |
| SCHEMBL6661794 | 0.84 | CTSB (0.51) | CTSBCTSLCTSSMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014882-A2 | PROTEASOME INHIBITORS : PEPTIDE DERIVATIVES HAVING C-TERMINAL HETEROARYL GROUPS | AXYS PHARMACEUTICALS (US) | 2004-02-19 | — | — | WO | disclosed |