Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | TACR2 | P21452 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6662955 | 0.96 | HTR2A (0.42) | HTR2AFAAHALDH1A1ESR1ADRA2A | |
| SCHEMBL6662750 | 0.93 | HTR2A (0.40) | HTR2AFAAHALDH1A1ESR1ADRA2A | |
| SCHEMBL6661968 | 0.93 | HTR2A (0.40) | HTR2AFAAHALDH1A1ESR1ADRA2A | |
| SCHEMBL6666975 | 0.92 | FAAH (0.43) | HTR2AFAAHALDH1A1ESR1ADRA2A | |
| SCHEMBL6663070 | 0.91 | HTR2A (0.39) | HTR2AKMT2AFAAHALDH1A1ESR1 | |
| SCHEMBL6660765 | 0.90 | MEN1 (0.42) | MEN1KMT2AKCNH2TMEM97TAAR1 | |
| SCHEMBL6663838 | 0.87 | PDE2A (0.39) | HTR2AMEN1KMT2AFAAHHDAC1 | |
| SCHEMBL6662969 | 0.86 | FAAH (0.41) | HTR2AMEN1KMT2AFAAHHDAC1 | |
| SCHEMBL6667590 | 0.86 | FAAH (0.41) | HTR2AMEN1KMT2AFAAHHDAC1 | |
| SCHEMBL6664177 | 0.86 | FAAH (0.41) | HTR2AMEN1KMT2AFAAHHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893423-B1 | LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES | CHISSO CORP (JP) | 2004-09-01 | — | — | EP | disclosed |