SCHEMBL6661987

SCHEMBL6661987

Fc1cccc(CI)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6487330 0.81 TAAR1 (0.63)
SCHEMBL646951 0.81 ALDH1A1 (0.43)
SCHEMBL94694 0.80
SCHEMBL3371633 0.79 TAAR1 (0.74)
SCHEMBL3300303 0.79 TAAR1 (0.60)
SCHEMBL17117518 0.78 TAAR1 (0.59)
SCHEMBL16213517 0.78 MAOB (0.73)
SCHEMBL9971249 0.77
SCHEMBL19615043 0.77
SCHEMBL283775 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111527096-B Compound and organic light emitting device comprising the same 株式会社LG化学 2023-10-27 CN disclosed
CN-113149971-B 8- (indoletriazole) substituted coumarin compound and preparation method and application thereof 港科鹏禾生物(苏州)有限公司 2022-12-16 CN disclosed
CN-113149971-A 8- (indoletriazole) substituted coumarin compound and preparation method and application thereof 港科鹏禾生物(苏州)有限公司 2021-07-23 CN disclosed
WO-2020064009-A1 SUBSTITUTED PYRAZOLE FUSED RING DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 北京志健金瑞生物医药科技有限公司 2020-04-02 WO disclosed
EP-3176163-B1 NOVEL INDENE DERIVATIVE, PREPARATION METHOD FOR SAME, AND PHARMACEUTICAL COMPOSITION, FOR PREVENTING OR TREATING RETINAL DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT IAC IN NAT UNIV CHUNGNAM (KR) 2019-04-17 EP disclosed
CN-105339334-B The method of Slight branching hydrophobe and corresponding surfactant and its application for preparing 陶氏环球技术有限责任公司 2017-10-24 CN disclosed
WO-2017117687-A1 18/19F-LABELLED COMPOUNDS WHICH TARGET THE PROSTATE SPECIFIC MEMBRANE ANTIGEN BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) 2017-07-13 WO disclosed
EP-2432321-B1 THIAZOLOPYRIMIDINONE DERIVATIVES AS PI3 KINASE INHIBITORS GLAXOSMITHKLINE LLC (US) 2017-06-14 EP disclosed
EP-3176163-A1 NOVEL INDENE DERIVATIVE, PREPARATION METHOD FOR SAME, AND PHARMACEUTICAL COMPOSITION, FOR PREVENTING OR TREATING RETINAL DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT The Industry & Academic Cooperation in Chungnam National University (IAC) (KR) 2017-06-07 EP disclosed
US-9475757-B2 Synthesis of anti-Parkinson agent COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2016-10-25 US disclosed
US-20020165397-A1 2-Pyridylsilane, processes for producing and using the same SUMITOMO CHEMICAL CO., LTD. 2002-11-07 US disclosed
CN-1332753-A Process for producing polyethylene EASTMAN CHEM CO (US) 2002-01-23 CN disclosed
US-20020007024-A1 Contacting ethylene and/or ethylene and one other olefin under polymerization conditions with a Ziegler-Natta type catalyst, a halogenated hydrocarbon, a co-catalyst WESTLAKE LONGVIEW CORPORATION 2002-01-17 US disclosed
EP-1159314-A1 PROCESS FOR PRODUCING POLYETHYLENE EASTMAN CHEMICAL COMPANY (US) 2001-12-05 EP disclosed
EP-1035125-A2 2-Pyridylsilane, processes for producing and using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-09-13 EP disclosed
WO-2000052067-A1 PROCESS FOR PRODUCING POLYETHYLENE EASTMAN CHEMICAL COMPANY (US) 2000-09-08 WO disclosed
US-5173496-A Antiinflammatory agents ICI PHARMA (FR) 1992-12-22 US disclosed
EP-0284174-B1 THERAPEUTIC PREPARATIONS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-07-29 EP disclosed
WO-1992002513-A1 HETEROCYCLIC COMPOUNDS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-02-20 WO disclosed
EP-0284174-A1 Therapeutic preparations IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-09-28 EP disclosed