Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | AGXT | P21549 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17117518 | 0.87 | TAAR1 (0.59) | TAAR1SLC6A3IDO1AGXTDRD2 | |
| SCHEMBL3371633 | 0.85 | TAAR1 (0.74) | TAAR1ALDH1A1SLC6A3IDO1AGXT | |
| SCHEMBL8591746 | 0.84 | TAAR1 (0.65) | TAAR1ALDH1A1SLC6A3IDO1AGXT | |
| SCHEMBL22288272 | 0.83 | ALDH1A1 (0.68) | TAAR1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL1047252 | 0.82 | TAAR1 (0.63) | TAAR1SLC6A3IDO1AGXTDRD2 | |
| SCHEMBL6661987 | 0.81 | — | — | |
| SCHEMBL144864 | 0.79 | TAAR1 (0.72) | TAAR1SLC6A3IDO1AGXTDRD2 | |
| SCHEMBL28812860 | 0.78 | TAAR1 (0.70) | TAAR1SLC6A3IDO1AGXTDRD2 | |
| SCHEMBL1047725 | 0.78 | TAAR1 (0.59) | TAAR1SLC6A3IDO1AGXTDRD2 | |
| SCHEMBL4869087 | 0.77 | TAAR1 (0.63) | TAAR1ALDH1A1SLC6A3IDO1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111220715-A | Method for separating and measuring safinamide mesylate and related substances thereof by liquid chromatography | 万全万特制药（厦门）有限公司 | 2020-06-02 | — | — | CN | disclosed |
| US-9505753-B2 | Inhibitors of D-amino acid oxidase | THE JOHNS HOPKINS UNIVERSITY (US) | 2016-11-29 | — | — | US | disclosed |
| US-20150218156-A1 | INHIBITORS OF D-AMINO ACID OXIDASE | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-08-06 | — | — | US | disclosed |
| WO-2014025993-A1 | INHIBITORS OF D-AMINO ACID OXIDASE | THE JOHNS HOPKINS UNIVERSITY (US) | 2014-02-13 | — | — | WO | disclosed |
| WO-2010021149-A1 | SPIRO COMPOUND CAPABLE OF INHIBITING ACID SECRETION | 武田薬品工業株式会社 (JP) | 2010-02-25 | — | — | WO | disclosed |
| US-20050240034-A1 | Artemisinin-based peroxide compounds as broad spectrum anti-infective agents | MISSISSIPPI, THE UNIVERSITY OF | 2005-10-27 | — | — | US | disclosed |
| WO-2003095444-A1 | ARTEMISININ-BASED PEROXIDE COMPOUNDS AS BROAD SPECTRUM ANTI-INFECTIVE AGENTS | UNIVERSITY OF MISSISSIPI (US) | 2003-11-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150218156-A1 | INHIBITORS OF D-AMINO ACID OXIDASE | DDO, DAO, GRIN2A | TAAR1 300/4885ALDH1A1 1465/4885HPGD 323/4885 |
| US-20050240034-A1 | Artemisinin-based peroxide compounds as broad spectrum anti-infective agents | CASP10, HCCS, CASP9 | TAAR1 4461/4885ALDH1A1 192/4885HPGD 449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.