Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29740662 | 0.87 | MAPT (0.57) | MAPTL3MBTL1ATMKCNH2ALDH1A1 | |
| SCHEMBL5692166 | 0.84 | MAPT (0.62) | MAPTL3MBTL1ATMKCNH2ALDH1A1 | |
| SCHEMBL160430 | 0.83 | ALDH1A1 (0.57) | MAPTL3MBTL1ATMALDH1A1MEN1 | |
| SCHEMBL4717364 | 0.82 | MAPT (0.56) | MAPTL3MBTL1ATMALDH1A1MEN1 | |
| Ethane SCHEMBL3302283 | 0.82 | MAPT (0.60) | MAPTL3MBTL1ATMKCNH2ALDH1A1 | |
| SCHEMBL12004712 | 0.81 | MAPT (0.55) | MAPTL3MBTL1ATMKCNH2ALDH1A1 | |
| SCHEMBL5835749 | 0.81 | MAPT (0.73) | MAPTL3MBTL1ATMKCNH2ALDH1A1 | |
| SCHEMBL13292848 | 0.81 | MAPT (0.58) | MAPTL3MBTL1ATMKCNH2ALDH1A1 | |
| SCHEMBL10490273 | 0.79 | ALDH1A1 (0.53) | MAPTL3MBTL1ATMALDH1A1MEN1 | |
| SCHEMBL3691462 | 0.78 | MAPT (0.64) | MAPTL3MBTL1ATMKCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265846-B1 | IMPROVED SYNTHESIS OF N,N-DISUBSTITUTED-p-PHENYLENEDIAMINE | ANTICANCER INC (US) | 2004-06-23 | — | — | EP | disclosed |
| EP-1265846-A1 | IMPROVED SYNTHESIS OF N,N-DISUBSTITUTED-p-PHENYLENEDIAMINE | Anticancer, Inc. (US) | 2002-12-18 | — | — | EP | disclosed |
| US-6448446-B1 | ONCE THE PRODUCT DSPDA OR ITS SALT IS FORMED, OXYGEN MUST BE EXCLUDED FROM ALL MANIPULATIONS. | ANTICANCER, INC. | 2002-09-10 | — | — | US | disclosed |
| US-20020026080-A1 | Synthesis of N,N-disubstituted-p-phenylenediamine | ANTICANCER, INC. | 2002-02-28 | — | — | US | disclosed |
| WO-2001051452-A1 | IMPROVED SYNTHESIS OF N,N-DISUBSTITUTED-p-PHENYLENEDIAMINE | ANTICANCER, INC. (US) | 2001-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020026080-A1 | Synthesis of N,N-disubstituted-p-phenylenediamine | QDPR, PNMT, DDT | MAPT 4273/4885L3MBTL1 3381/4885ATM 2313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.