SCHEMBL6662201

SCHEMBL6662201

CN(C)/C=N\c1ccc(O)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100B P04271 3/20 0.62
KMT2A Q03164 5/20 0.52
APP P05067 1/20 0.42
ALDH1A1 P00352 4/20 0.42
HSD17B10 Q99714 4/20 0.42
MEN1 O00255 4/20 0.42
MAPT P10636 3/20 0.42
ALOX15 P16050 3/20 0.42
L3MBTL1 Q9Y468 3/20 0.42
LMNA P02545 2/20 0.42
POLB P06746 2/20 0.42
BLM P54132 2/20 0.42
THRB P10828 2/20 0.42
GAA P10253 2/20 0.42
CASP1 P29466 2/20 0.42
USP2 O75604 1/20 0.42
HTT P42858 1/20 0.42
RECQL P46063 1/20 0.42
SAE1 Q9UBE0 1/20 0.42
UBA2 Q9UBT2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11666035 1.00 S100B (0.62) S100BKMT2AAPPALDH1A1HSD17B10
SCHEMBL6659427 1.00 S100B (0.62) S100BKMT2AAPPALDH1A1HSD17B10
SCHEMBL17828618 0.79 ALDH1A1 (0.55) KMT2AALDH1A1HSD17B10MEN1MAPT
SCHEMBL218111 0.76 ALDH1A1 (0.53) KMT2AALDH1A1HSD17B10MEN1MAPT
SCHEMBL218110 0.76 ALDH1A1 (0.53) KMT2AALDH1A1HSD17B10MEN1MAPT
SCHEMBL17761949 0.76 ALDH1A1 (0.53) KMT2AALDH1A1HSD17B10MEN1MAPT
SCHEMBL10342089 0.76 KMT2A (0.50) S100BKMT2AALDH1A1HSD17B10MEN1
SCHEMBL17828616 0.76 KMT2A (0.50) S100BKMT2AALDH1A1HSD17B10MEN1
SCHEMBL17828615 0.76 KMT2A (0.50) S100BKMT2AALDH1A1HSD17B10MEN1
SCHEMBL11412530 0.75 KMT2A (0.50) S100BKMT2AALDH1A1HSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0977552-B1 COMPOSITION FOR TOPICAL APPLICATION ON THE SKIN AND/OR ITS APPENDAGES COMPRISING AT LEAST A COMPOUND CONTAINING AN IMINOPHENOL FRAGMENT OREAL (FR) 2004-08-11 EP claimed
US-6514486-B1 Inhibits tyrosinase or the synthesis of melanin; N'-(4-hydroxyphenyl)-N,N-dimethylformamidine L'OREAL (FR) 2003-02-04 US claimed
US-6514486-B1 Inhibits tyrosinase or the synthesis of melanin; N'-(4-hydroxyphenyl)-N,N-dimethylformamidine L'OREAL (FR) 2003-02-04 US disclosed