Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6663312 | 0.88 | PPARG (0.39) | LMNAPOLBPPARGPPARAMAPK1 | |
| SCHEMBL6660730 | 0.85 | PPARA (0.42) | LMNAPOLBPPARAMAPK1SMN1; SMN2 | |
| SCHEMBL6664949 | 0.83 | TSHR (0.45) | LMNARXRAGRIN1GRIN2BRXRB | |
| SCHEMBL257110 | 0.82 | PPARG (0.50) | LMNAPOLBPPARGPPARARXRA | |
| SCHEMBL6661347 | 0.80 | FFAR4 (0.33) | LMNAALDH1A1 | |
| SCHEMBL6661309 | 0.79 | CACNA1H (0.34) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL6667004 | 0.79 | LMNA (0.47) | LMNAPTPN1ALDH1A1MAPT | |
| SCHEMBL6665156 | 0.79 | CYP2C9 (0.41) | LMNAPOLBMAPK1ACACBALDH1A1 | |
| SCHEMBL6662034 | 0.78 | IDO1 (0.50) | PPARGPTPN1MAPT | |
| SCHEMBL6666035 | 0.78 | TAAR1 (0.38) | POLBRXRARXRBSMN1; SMN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893423-B1 | LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES | CHISSO CORP (JP) | 2004-09-01 | — | — | EP | disclosed |