Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6660730 | 0.91 | PPARA (0.42) | PPARALMNAPOLBDAOBACE1 | |
| SCHEMBL6662935 | 0.88 | LMNA (0.39) | PPARGPPARALMNAPOLBDAO | |
| SCHEMBL6661132 | 0.86 | LPL (0.38) | LMNAPOLBTHRBALDH1A1GAA | |
| SCHEMBL8342798 | 0.83 | PPARG (0.50) | PPARGPPARALMNAPOLBDAO | |
| SCHEMBL6666711 | 0.82 | TSHR (0.42) | LMNADAOTHRBALDH1A1 | |
| SCHEMBL6666035 | 0.82 | TAAR1 (0.38) | POLBTHRBALDH1A1GAAMAPT | |
| SCHEMBL6662007 | 0.81 | CACNA1H (0.34) | — | |
| SCHEMBL6664047 | 0.81 | GPR84 (0.30) | — | |
| SCHEMBL6661146 | 0.80 | ALDH1A1 (0.42) | LMNAKMT2AALDH1A1GAA | |
| SCHEMBL6665156 | 0.79 | CYP2C9 (0.41) | LMNAPOLBMAPK1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893423-B1 | LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES | CHISSO CORP (JP) | 2004-09-01 | — | — | EP | disclosed |