Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6414859 | 0.92 | MEN1 (0.46) | SCN9AELANEKDM4EKMT2AHSD17B10 | |
| Trifluoroacetic Acid SCHEMBL6654304 | 0.82 | SPHK1 (0.43) | SCN9AELANEKDM4EALDH1A1AR | |
| Trifluoroacetic Acid SCHEMBL6658125 | 0.81 | AKR1C3 (0.40) | SCN9ARAB9AL3MBTL1SPHK1HPGD | |
| SCHEMBL6656271 | 0.74 | ALDH1A1 (0.49) | SCN9AELANEKDM4EALDH1A1AR | |
| SCHEMBL6417166 | 0.71 | L3MBTL1 (0.46) | SCN9AELANERAB9AL3MBTL1SPHK1 | |
| Trifluoroacetic Acid SCHEMBL6418154 | 0.70 | KDM4E (0.42) | KDM4EKMT2AHSD17B10MEN1ALDH1A1 | |
| SCHEMBL6417173 | 0.68 | KMT2A (0.57) | KMT2AHSD17B10MEN1ALDH1A1RAB9A | |
| SCHEMBL8370633 | 0.68 | KMT2A (0.59) | KMT2AHSD17B10MEN1ALDH1A1RAB9A | |
| SCHEMBL18474160 | 0.67 | DPP4 (0.45) | ELANEKMT2AMEN1ALDH1A1AR | |
| SCHEMBL18474217 | 0.67 | DPP4 (0.45) | ELANEKMT2AMEN1ALDH1A1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1434580-A2 | ALLYLAMIDES USEFUL IN THE TREATMENT OF ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2004-07-07 | — | — | EP | disclosed |
| WO-2003030886-A2 | ALLYLAMIDES USEFUL IN THE TREATMENT OF ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC (US) | 2003-04-17 | — | — | WO | disclosed |
| CN-1090186-C | HIV protease inhibitors in pharmaceutical combinations for the treatment of AIDS | MERCK & CO INC (US) | 2002-09-04 | — | — | CN | disclosed |
| CN-1176250-A | HIV protease inhibitors useful for treatment of AIDS | MERCK & CO INC (US) | 1998-03-18 | — | — | CN | disclosed |
| CN-1126469-A | HIV protease inhibitors for the treatment of AIDS | MERCK & CO INC (US) | 1996-07-10 | — | — | CN | disclosed |