SCHEMBL6663310

SCHEMBL6663310

CCCc1ccc(C(F)(F)OC(C)c2ccc(OC(F)F)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.37
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36
FFAR1 O14842 1/20 0.36
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
ACACB O00763 3/20 0.35
ACACA Q13085 1/20 0.35
PSMB5 P28074 1/20 0.34
PTGDR2 Q9Y5Y4 1/20 0.34
HTT P42858 1/20 0.33
SRD5A1 P18405 1/20 0.33
SRD5A2 P31213 1/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
BACE1 P56817 1/20 0.32
MAPT P10636 1/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6660727 0.91 PPARA (0.39) DAOPPARAFFAR1KMT2AMEN1
SCHEMBL6662930 0.90 PPARG (0.35) DAOPPARGPPARAKMT2AMEN1
SCHEMBL6661128 0.89 KMT2A (0.36) KMT2AMEN1ACACBACACAPSMB5
SCHEMBL6666707 0.86 PDE2A (0.42) DAOKMT2AMEN1ACACBACACA
SCHEMBL6660765 0.85 MEN1 (0.42) PPARGPPARAKMT2AMEN1PSMB5
SCHEMBL6666034 0.85 TSHR (0.34) PPARGPPARAKMT2AMEN1ACACB
SCHEMBL6661144 0.84 KMT2A (0.43) KMT2AMEN1ACACBACACAPSMB5
SCHEMBL6662750 0.83 HTR2A (0.40) LMNA
SCHEMBL6661968 0.83 HTR2A (0.40) LMNA
SCHEMBL7732775 0.82 PPARG (0.40) DAOPPARGPPARAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0893423-B1 LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES CHISSO CORP (JP) 2004-09-01 EP disclosed