SCHEMBL6666034

SCHEMBL6666034

CCCc1ccc(C(C)OC(F)(F)c2ccc(CC)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.34
MAPK1 P28482 1/20 0.34
ATM Q13315 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
ACACB O00763 2/20 0.33
ALDH1A1 P00352 2/20 0.33
TAAR1 Q96RJ0 2/20 0.33
LMNA P02545 1/20 0.33
ACACA Q13085 1/20 0.33
PSMB5 P28074 1/20 0.33
KCNH2 Q12809 1/20 0.33
TMEM97 Q5BJF2 1/20 0.33
SIGMAR1 Q99720 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6661128 0.95 KMT2A (0.36) KMT2AMEN1ACACBALDH1A1TAAR1
SCHEMBL6660765 0.91 MEN1 (0.42) TSHRKMT2AMEN1ALDH1A1TAAR1
SCHEMBL6666975 0.90 FAAH (0.43) ALDH1A1LMNACYP3A4
SCHEMBL6661144 0.90 KMT2A (0.43) MAPK1TDP1L3MBTL1KMT2AMEN1
SCHEMBL6666707 0.89 PDE2A (0.42) TSHRKMT2AMEN1ACACBALDH1A1
SCHEMBL6661968 0.89 HTR2A (0.40) ALDH1A1LMNASIGMAR1CYP3A4
SCHEMBL6662750 0.89 HTR2A (0.40) ALDH1A1LMNASIGMAR1CYP3A4
SCHEMBL6662033 0.88 ALDH1A1 (0.42) TSHRMAPK1ATMTDP1L3MBTL1
SCHEMBL6667003 0.87 LMNA (0.46) TSHRMAPK1ATMTDP1L3MBTL1
SCHEMBL6662955 0.85 HTR2A (0.42) ALDH1A1LMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0893423-B1 LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES CHISSO CORP (JP) 2004-09-01 EP disclosed