Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ADH1A | P07327 | 3/20 | 0.32 |
| ▸ | ADH1C | P00326 | 2/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | ADH4 | P08319 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL6659361 | 0.95 | CYP1A2 (0.38) | CYP1A2ADH1AADH1CGBA1ADH4 | |
| SCHEMBL6659181 | 0.95 | CYP1A2 (0.41) | CYP1A2ADH1AADH1CGBA1ADH4 | |
| SCHEMBL6744902 | 0.93 | CYP1A2 (0.39) | CYP1A2ADH1AADH1CGBA1ADH4 | |
| SCHEMBL19773375 | 0.86 | CYP1A2 (0.38) | CYP1A2ADH1AADH1CGBA1ADH4 | |
| Hydrochloric Acid SCHEMBL6663721 | 0.86 | ADH1A (0.39) | ADH1AADH1CSIGMAR1 | |
| SCHEMBL19773294 | 0.83 | CYP1A2 (0.35) | CYP1A2ADH1AADH1CGBA1SIGMAR1 | |
| SCHEMBL1517550 | 0.81 | THRB (0.35) | CYP1A2 | |
| SCHEMBL8397229 | 0.81 | SLC18A3 (0.41) | CYP1A2GBA1 | |
| SCHEMBL8397230 | 0.81 | SLC18A3 (0.41) | CYP1A2GBA1 | |
| SCHEMBL8397232 | 0.81 | SLC18A3 (0.41) | CYP1A2GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1160267-B1 | CATALYST FOR OXIDATIVE POLYMERIZATION OF FLUOROPHENOL, METHOD OF OXIDATIVE POLYMERIZATION OF FLUOROPHENOL, AND POLY(OXYFLUOROPHENYLENE) DERIVATIVE | JAPAN SCIENCE & TECH CORP (JP) | 2004-08-04 | — | — | EP | disclosed |