Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28775122 | 0.91 | HTR6 (0.34) | HTR6HTR2CDPP4 | |
| SCHEMBL4630524 | 0.82 | HTR6 (0.43) | HTR6HTR2C | |
| SCHEMBL4630618 | 0.80 | HTR6 (0.44) | HTR6HTR2C | |
| SCHEMBL8146446 | 0.76 | HTR6 (0.47) | HTR6HTR2C | |
| SCHEMBL29118976 | 0.73 | HTR6 (0.48) | HTR6HTR2C | |
| SCHEMBL17048236 | 0.72 | HTR6 (0.47) | HTR6HTR2C | |
| SCHEMBL10465527 | 0.72 | HTR6 (0.47) | HTR6HTR2C | |
| SCHEMBL2981611 | 0.71 | HRH3 (0.34) | DPP4 | |
| SCHEMBL2990654 | 0.71 | DPP7 (0.35) | DPP4 | |
| SCHEMBL2990655 | 0.71 | DPP7 (0.35) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465867-A1 | LIGANDS OF MELANOCORTIN RECEPTORS AND COMPOSITIONS AND METHODS RELATED THERETO | Neurocrine Biosciences, Inc. (US) | 2004-10-13 | — | — | EP | disclosed |
| US-20030158209-A1 | Ligands of melanocortin receptors and compositions and methods related thereto | NEUROCRINE BIOSCIENCES INC. | 2003-08-21 | — | — | US | disclosed |
| WO-2003031410-A1 | LIGANDS OF MELANOCORTIN RECEPTORS AND COMPOSITIONS AND METHODS RELATED THERETO | NEUROCRINE BIOSCIENCES, INC. (US) | 2003-04-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158209-A1 | Ligands of melanocortin receptors and compositions and methods related thereto | MC3R, MC1R, MC4R | HTR6 153/4885HTR2C 96/4885DPP4 2060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.