Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.51 |
| ▸ | NT5E | P21589 | 5/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7067579 | 0.91 | ADORA3 (0.61) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL7068557 | 0.90 | ADORA3 (0.54) | ADORA3ADORA1NT5EADORA2AADORA2B | |
| SCHEMBL7067807 | 0.85 | ADORA1 (0.58) | ADORA3ADORA1NT5EADORA2AADORA2B | |
| SCHEMBL7067811 | 0.85 | ADORA1 (0.58) | ADORA3ADORA1NT5EADORA2AADORA2B | |
| SCHEMBL6663637 | 0.81 | ADORA3 (0.72) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL7064488 | 0.81 | ADORA3 (0.65) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL6660843 | 0.76 | ADORA3 (0.81) | ADORA3ADORA1NT5EADORA2AADORA2B | |
| SCHEMBL6660828 | 0.76 | ADORA3 (0.81) | ADORA3ADORA1NT5EADORA2AADORA2B | |
| SCHEMBL12610019 | 0.74 | ADORA3 (0.81) | ADORA3ADORA1NT5EADORA2AADORA2B | |
| SCHEMBL19799156 | 0.73 | ADORA3 (0.79) | ADORA3ADORA1ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027363-B1 | ADENOSINE A1-RECEPTOR AGONISTS | GLAXO GROUP LTD (GB) | 2003-06-04 | — | — | EP | claimed |